How Do Trypanosomes Change Gene Expression in Response to the Environment?

Overview

Journal Protoplasma

Publisher Springer

Specialty Biology

Date 2011 May 20

PMID 21594757

Citations 19

Authors

Angela Schwede

Susanne Kramer

Mark Carrington

Affiliations

Soon will be listed here.

Abstract

All organisms are able to modulate gene expression in response to internal and external stimuli. Trypanosomes represent a group that diverged early during the radiation of eukaryotes and do not utilise regulated initiation of transcription by RNA polymerase II. Here, the mechanisms present in trypanosomes to alter gene expression in response to stress and change of host environment are discussed and contrasted with those operating in yeast and cultured mammalian cells.

Citing Articles

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Domain function and predicted structure of three heterodimeric endonuclease subunits of RNA editing catalytic complexes in Trypanosoma brucei.

Carnes J, McDermott S, Lewis I, Tracy M, Stuart K Nucleic Acids Res. 2022; 50(17):10123-10139.

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Ubiquitin-Like Modifiers: Emerging Regulators of Protozoan Parasites.

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Trypanosomatid selenophosphate synthetase structure, function and interaction with selenocysteine lyase.

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