Nutritional Status Driving Infection by Trypanosoma Cruzi: Lessons from Experimental Animals

Overview

Journal J Trop Med

Publisher Wiley

Specialty Tropical Medicine

Date 2011 May 18

PMID 21577255

Citations 4

Authors

Guilherme Malafaia

Andre Talvani

Affiliations

Soon will be listed here.

Abstract

This paper reviews the scientific knowledge about protein-energy and micronutrient malnutrition in the context of Chagas disease, especially in experimental models. The search of articles was conducted using the electronic databases of SciELO (Scientific Electronic Library Online), PubMed and MEDLINE published between 1960 and March 2010. It was possible to verify that nutritional deficiencies (protein-energy malnutrition and micronutrient malnutrition) exert a direct effect on the infection by T. cruzi. However, little is known about the immunological mechanisms involved in the relationship "nutritional deficiencies and infection by T. cruzi". A hundred years after the discovery of Chagas disease many aspects of this illness still require clarification, including the effects of nutritional deficiencies on immune and pathological mechanisms of T. cruzi infection.

Citing Articles

Small molecule mediators of host-T. cruzi-environment interactions in Chagas disease.

Kwakye-Nuako G, Middleton C, McCall L PLoS Pathog. 2024; 20(3):e1012012.

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Elevated Pediatric Chagas Disease Burden Complicated by Concomitant Intestinal Parasites and Malnutrition in El Salvador.

Nolan M, Murray K, Mejia R, Hotez P, Villar Mondragon M, Rodriguez S Trop Med Infect Dis. 2021; 6(2).

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Effects of ghrelin supplementation on the acute phase of Chagas disease in rats.

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Anti-trypanosomal effect of Peristrophe bicalyculata extract on Trypanosoma brucei brucei-infected rats.

Abimbola A, Baba I, Yenusa E, Omanibe S, Oladimeji I Asian Pac J Trop Biomed. 2013; 3(7):523-31.

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