» Articles » PMID: 21562671

Differential Nano-bio Interactions and Toxicity Effects of Pristine Versus Functionalized Graphene

Overview
Journal Nanoscale
Specialty Biotechnology
Date 2011 May 13
PMID 21562671
Citations 114
Authors
Affiliations
Soon will be listed here.
Abstract

We report the effect of carboxyl functionalization of graphene in pacifying its strong hydrophobic interaction with cells and associated toxic effects. Pristine graphene was found to accumulate on the cell membrane causing high oxidative stress leading to apoptosis, whereas carboxyl functionalized hydrophilic graphene was internalized by the cells without causing any toxicity.

Citing Articles

Non-Cytotoxic Graphene Nanoplatelets Upregulate Cell Proliferation and Self-Renewal Genes of Mesenchymal Stem Cells.

Nicoletti N, Marinowic D, Perondi D, Goncalves J, Piazza D, Da Costa J Int J Mol Sci. 2024; 25(18).

PMID: 39337305 PMC: 11431873. DOI: 10.3390/ijms25189817.


Emerging 2D Nanomaterials-Integrated Hydrogels: Advancements in Designing Theragenerative Materials for Bone Regeneration and Disease Therapy.

Zorron M, Cabrera A, Sharma R, Radhakrishnan J, Abbaszadeh S, Shahbazi M Adv Sci (Weinh). 2024; 11(31):e2403204.

PMID: 38874422 PMC: 11336986. DOI: 10.1002/advs.202403204.


Applications of Graphene Family Nanomaterials in Regenerative Medicine: Recent Advances, Challenges, and Future Perspectives.

Chen X, Zou M, Liu S, Cheng W, Guo W, Feng X Int J Nanomedicine. 2024; 19:5459-5478.

PMID: 38863648 PMC: 11166159. DOI: 10.2147/IJN.S464025.


Ten years of laser-induced graphene: impact and future prospect on biomedical, healthcare, and wearable technology.

Thaweeskulchai T, Sakdaphetsiri K, Schulte A Mikrochim Acta. 2024; 191(5):292.

PMID: 38687361 DOI: 10.1007/s00604-024-06350-z.


Bioscaffolds of graphene based-polymeric hybrid materials for myocardial tissue engineering.

Amiryaghoubi N, Fathi M Bioimpacts. 2024; 14(1):27684.

PMID: 38327630 PMC: 10844587. DOI: 10.34172/bi.2023.27684.