» Articles » PMID: 21560178

Free Flap Reconstruction of Osteoradionecrosis of the Mandible: a 10-year Review and Defect Classification

Overview
Journal Head Neck
Date 2011 May 12
PMID 21560178
Citations 19
Authors
Affiliations
Soon will be listed here.
Abstract

Background: The purpose of this study was to evaluate outcomes of free flap reconstruction for advanced osteoradionecrosis (ORN) defects and develop an algorithm to guide surgical planning.

Methods: All cases involving free flap reconstruction for ORN of the mandible between 1998 and 2008 were reviewed. A defect classification scheme was developed. Flap selection and outcomes were analyzed and evaluated by defect type.

Results: Seventy-five free flaps and 13 pedicle flaps were performed in 63 patients. Total flap loss was 5%. Overall surgical complication was 32%. Complication rates were higher with bone flaps than with soft tissue flaps (p = .018). A full oral diet was tolerated in 57% of patients, whereas 26% required partial tube feeding, and 16% were tube-feeding dependent.

Conclusion: Free flap reconstruction of advanced ORN defects can be safely performed in a variety of flap configurations with good outcomes. The classification scheme may assist in flap selection.

Citing Articles

Managing Mandibular Osteoradionecrosis.

Fritz M, Arianpour K, Liu S, Lamarre E, Genther D, Ciolek P Otolaryngol Head Neck Surg. 2024; 172(2):406-418.

PMID: 39327863 PMC: 11773448. DOI: 10.1002/ohn.990.


Therapeutic potential of carbon dots from in radiation-induced bone injury.

Khajuria D, Karasik D Ann Transl Med. 2024; 12(3):56.

PMID: 38911558 PMC: 11193556. DOI: 10.21037/atm-24-10.


Prevalence of free flap failure in mandibular osteoradionecrosis reconstruction: a systematic review and meta-analysis.

Kostares E, Kostares M, Kostare G, Tsakris A, Kantzanou M Sci Rep. 2024; 14(1):11087.

PMID: 38750124 PMC: 11096303. DOI: 10.1038/s41598-024-61862-1.


Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation of a Risk-Based Model.

Watson E, Hueniken K, Lee J, Huang S, El Maghrabi A, Xu W J Clin Oncol. 2024; 42(16):1922-1933.

PMID: 38691822 PMC: 11500043. DOI: 10.1200/JCO.23.01951.


Prophylactic Use of Pentoxifylline and Tocopherol for Prevention of Osteoradionecrosis of the Jaw after Dental Extraction in Post-Radiated Oral and Oropharyngeal Cancer Patients: An Initial Case Series.

Owosho A, DeColibus K, Okhuaihesuyi O, Levy L Dent J (Basel). 2024; 12(4).

PMID: 38667995 PMC: 11049290. DOI: 10.3390/dj12040083.