Balancing the Risks and Benefits of Proton Pump Inhibitors

Overview

Journal Ann Fam Med

Specialty Public Health

Date 2011 May 11

PMID 21555747

Citations 3

Authors

James M Gill

Marty S Player

David C Metz

Affiliations

Soon will be listed here.

Citing Articles

Comparing the Safety and Efficacy of Proton Pump Inhibitors and Histamine-2 Receptor Antagonists in the Management of Patients With Peptic Ulcer Disease: A Systematic Review.

Begg M, Tarhuni M, Fotso M, Gonzalez N, Sanivarapu R, Osman U Cureus. 2023; 15(8):e44341.

PMID: 37779765 PMC: 10538946. DOI: 10.7759/cureus.44341.

Improving prescribing for older patients - 'Yes S-I-R-E!'.

Cheong T, Alhamid S, Li F, Ang S, Lim K Singapore Med J. 2018; 60(6):298-302.

PMID: 30488080 PMC: 6595067. DOI: 10.11622/smedj.2018153.

Discontinuing Long-Term PPI Therapy: Why, With Whom, and How?.

Targownik L Am J Gastroenterol. 2018; 113(4):519-528.

PMID: 29557943 DOI: 10.1038/ajg.2018.29.

References

Talley N . American Gastroenterological Association medical position statement: evaluation of dyspepsia. Gastroenterology. 2005; 129(5):1753-5. DOI: 10.1053/j.gastro.2005.09.019. View

Leonard J, Marshall J, Moayyedi P . Systematic review of the risk of enteric infection in patients taking acid suppression. Am J Gastroenterol. 2007; 102(9):2047-56. DOI: 10.1111/j.1572-0241.2007.01275.x. View

Metz D, Inadomi J, Howden C, Veldhuyzen van Zanten S, Bytzer P . On-demand therapy for gastroesophageal reflux disease. Am J Gastroenterol. 2006; 102(3):642-53. DOI: 10.1111/j.1572-0241.2006.00998.x. View

Targownik L, Lix L, Leung S, Leslie W . Proton-pump inhibitor use is not associated with osteoporosis or accelerated bone mineral density loss. Gastroenterology. 2009; 138(3):896-904. DOI: 10.1053/j.gastro.2009.11.014. View

Merriman N, Putt M, Metz D, Yang Y . Hip fracture risk in patients with a diagnosis of pernicious anemia. Gastroenterology. 2009; 138(4):1330-7. PMC: 2954457. DOI: 10.1053/j.gastro.2009.12.007. View

Player M, Gill J, Mainous 3rd A, Everett C, Koopman R, Diamond J . An electronic medical record-based intervention to improve quality of care for gastro-esophageal reflux disease (GERD) and atypical presentations of GERD. Qual Prim Care. 2010; 18(4):223-9. View

Yang Y, Lewis J, Epstein S, Metz D . Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA. 2006; 296(24):2947-53. DOI: 10.1001/jama.296.24.2947. View

Lanza F, Chan F, Quigley E . Guidelines for prevention of NSAID-related ulcer complications. Am J Gastroenterol. 2009; 104(3):728-38. DOI: 10.1038/ajg.2009.115. View

Wallace J . Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years. Gastroenterology. 1997; 112(3):1000-16. DOI: 10.1053/gast.1997.v112.pm9041264. View

10.

Poynard T, Lemaire M, Agostini H . Meta-analysis of randomized clinical trials comparing lansoprazole with ranitidine or famotidine in the treatment of acute duodenal ulcer. Eur J Gastroenterol Hepatol. 1995; 7(7):661-5. View

11.

Yang Y, Metz D . Safety of proton pump inhibitor exposure. Gastroenterology. 2010; 139(4):1115-27. DOI: 10.1053/j.gastro.2010.08.023. View

12.

Targownik L, Lix L, Metge C, Prior H, Leung S, Leslie W . Use of proton pump inhibitors and risk of osteoporosis-related fractures. CMAJ. 2008; 179(4):319-26. PMC: 2492962. DOI: 10.1503/cmaj.071330. View

13.

Wolfe M, Sachs G . Acid suppression: optimizing therapy for gastroduodenal ulcer healing, gastroesophageal reflux disease, and stress-related erosive syndrome. Gastroenterology. 2000; 118(2 Suppl 1):S9-31. DOI: 10.1016/s0016-5085(00)70004-7. View

14.

Gill J, Mainous 3rd A, Koopman R, Player M, Everett C, Chen Y . Impact of EHR-based clinical decision support on adherence to guidelines for patients on NSAIDs: a randomized controlled trial. Ann Fam Med. 2011; 9(1):22-30. PMC: 3022041. DOI: 10.1370/afm.1172. View

15.

van Marrewijk C, Mujakovic S, Fransen G, Numans M, de Wit N, Muris J . Effect and cost-effectiveness of step-up versus step-down treatment with antacids, H2-receptor antagonists, and proton pump inhibitors in patients with new onset dyspepsia (DIAMOND study): a primary-care-based randomised controlled trial. Lancet. 2009; 373(9659):215-25. DOI: 10.1016/S0140-6736(09)60070-2. View

16.

den Elzen W, Groeneveld Y, de Ruijter W, Souverijn J, le Cessie S, Assendelft W . Long-term use of proton pump inhibitors and vitamin B12 status in elderly individuals. Aliment Pharmacol Ther. 2008; 27(6):491-7. DOI: 10.1111/j.1365-2036.2008.03601.x. View

17.

DeVault K, Castell D . Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol. 2005; 100(1):190-200. DOI: 10.1111/j.1572-0241.2005.41217.x. View

18.

Eom C, Park S, Myung S, Yun J, Ahn J . Use of acid-suppressive drugs and risk of fracture: a meta-analysis of observational studies. Ann Fam Med. 2011; 9(3):257-67. PMC: 3090435. DOI: 10.1370/afm.1243. View

19.

Smalley W, Stein C, Arbogast P, Eisen G, Ray W, Griffin M . Underutilization of gastroprotective measures in patients receiving nonsteroidal antiinflammatory drugs. Arthritis Rheum. 2002; 46(8):2195-200. DOI: 10.1002/art.10425. View