» Articles » PMID: 21550765

Dilute Betadine Lavage Before Closure for the Prevention of Acute Postoperative Deep Periprosthetic Joint Infection

Overview
Journal J Arthroplasty
Specialty Orthopedics
Date 2011 May 10
PMID 21550765
Citations 66
Authors
Affiliations
Soon will be listed here.
Abstract

This study evaluated the efficacy of a dilute Betadine (Purdue Pharma, Stamford, Conn) lavage in preventing early deep postoperative infection after total hip (THA) and knee (TKA) arthroplasty. A protocol of dilute Betadine lavage (0.35%) for 3 minutes was introduced to the practice of the senior author in June 2008. A total of 1862 consecutive cases (630 THA and 1232 TKA) performed before this were compared with 688 consecutive cases (274 THA and 414 TKA) after for the occurrence of periprosthetic infections within the first 90 days postoperatively. Eighteen early postoperative infections were identified before the use of dilute Betadine lavage, and 1 since (0.97% and 0.15%, respectively; P = .04). There were no significant demographic differences between the 2 groups. Betadine lavage before wound closure may be an inexpensive, effective means of reducing acute postoperative infection after total joint arthroplasty.

Citing Articles

Total femur replacement in revision arthroplasty for non-oncologic patients: a systematic review.

Liu C, Ehlers C, Berger G, Ball S, Chiarappa F Eur J Orthop Surg Traumatol. 2025; 35(1):112.

PMID: 40074982 DOI: 10.1007/s00590-025-04226-3.


Dilute Povidone-Iodine Irrigation: The Science of Molecular Iodine (I2) Kinetics and Its Antimicrobial Activity.

Meehan J J Am Acad Orthop Surg. 2024; 33(2):65-73.

PMID: 39729104 PMC: 11661569. DOI: 10.5435/JAAOS-D-24-00471.


Periprosthetic joint infections: state-of-the-art.

Gehrke T, Citak M, Parvizi J, Budhiparama N, Akkaya M Arch Orthop Trauma Surg. 2024; 145(1):58.

PMID: 39694911 DOI: 10.1007/s00402-024-05627-5.


Systemic iodine levels increase with povidone-iodine irrigation, but does this affect thyroid functions? A case-control study.

Ertan M, Basarir K, Kocaoglu H, Aydugan M, Gungor E J Orthop Surg Res. 2024; 19(1):636.

PMID: 39380015 PMC: 11462707. DOI: 10.1186/s13018-024-04877-8.


Comparison of the effect of combined usage of povidone-iodine irrigation and topical vancomycin powder to the use of povidone-iodine irrigation alone on the periprosthetic joint infection incidence rate in patients undergoing primary total hip and....

Kulakowski M, Elster K, Szymczak M, Sleczka P, Baumgart M, Krolikowska A Trials. 2024; 25(1):468.

PMID: 38987786 PMC: 11234679. DOI: 10.1186/s13063-024-08306-3.