AtMYB2 Regulates Whole Plant Senescence by Inhibiting Cytokinin-mediated Branching at Late Stages of Development in Arabidopsis

Overview

Journal Plant Physiol

Specialty Physiology

Date 2011 May 6

PMID 21543729

Citations 64

Authors

Yongfeng Guo

Susheng Gan

Affiliations

Soon will be listed here.

Abstract

Whole plant senescence of monocarpic plants consists of three major processes: arrest of shoot apical meristem, organ senescence, and permanent suppression of axillary buds. At early stages of development, axillary buds are inhibited by shoot apex-produced auxin, a mechanism known as apical dominance. How the buds are suppressed as an essential part of whole plant senescence, especially when the shoot apexes are senescent, is not clear. Here, we report an AtMYB2-regulated post apical dominance mechanism by which Arabidopsis (Arabidopsis thaliana) inhibits the outgrowth of axillary buds as part of the whole plant senescence program. AtMYB2 is expressed in the compressed basal internode region of Arabidopsis at late stages of development to suppress the production of cytokinins, the group of hormones that are required for axillary bud outgrowth. atmyb2 T-DNA insertion lines have enhanced expression of cytokinin-synthesizing isopentenyltransferases genes, contain higher levels of cytokinins, and display a bushy phenotype at late stages of development. As a result of the continuous generation of new shoots, atmyb2 plants have a prolonged life span. The AtMYB2 promoter-directed cytokinin oxidase 1 gene in the T-DNA insertion lines reduces the endogenous cytokinin levels and restores the bushy phenotype to the wild type.

Citing Articles

Transcriptome and WGCNA reveals the potential genetic basis of photoperiod-sensitive male sterility in soybean.

Yang Y, He S, Xu L, Wang M, Chen S, Bai Z BMC Genomics. 2025; 26(1):131.

PMID: 39934659 PMC: 11816801. DOI: 10.1186/s12864-025-11314-5.

Physiological and molecular characteristics associated with the anti-senescence in Abel.

Zhang Z, Xu Y, He Z, Liu C, Wang R, Wang X Photosynthetica. 2024; 62(1):102-111.

PMID: 39650640 PMC: 11609776. DOI: 10.32615/ps.2024.003.

Non-additive expression genes play a critical role in leaf vein ratio heterosis in Nicotiana tabacum L.

Duan L, Mo Z, Li K, Pi K, Luo J, Que Y BMC Genomics. 2024; 25(1):924.

PMID: 39363277 PMC: 11451143. DOI: 10.1186/s12864-024-10821-1.

Comparative Effects of Water Scarcity on the Growth and Development of Two Common Bean ( L.) Genotypes with Different Geographic Origin (Mesoamerica/Andean).

Galan P, Ivanescu L, Leti L, Zamfirache M, Gorgan D Plants (Basel). 2024; 13(15).

PMID: 39124229 PMC: 11314307. DOI: 10.3390/plants13152111.

Overexpression of Promotes Tolerance to Salt Stress and Accumulations of Tanshinones and Phenolic Acid in .

Li T, Zhang S, Li Y, Zhang L, Song W, Chen C Int J Mol Sci. 2024; 25(7).

PMID: 38612919 PMC: 11012609. DOI: 10.3390/ijms25074111.

References

Umehara M, Hanada A, Yoshida S, Akiyama K, Arite T, Takeda-Kamiya N . Inhibition of shoot branching by new terpenoid plant hormones. Nature. 2008; 455(7210):195-200. DOI: 10.1038/nature07272. View

Sorefan K, Booker J, Haurogne K, Goussot M, Bainbridge K, Foo E . MAX4 and RMS1 are orthologous dioxygenase-like genes that regulate shoot branching in Arabidopsis and pea. Genes Dev. 2003; 17(12):1469-74. PMC: 196077. DOI: 10.1101/gad.256603. View

Napoli C, Beveridge C, Snowden K . Reevaluating concepts of apical dominance and the control of axillary bud outgrowth. Curr Top Dev Biol. 1999; 44:127-69. DOI: 10.1016/s0070-2153(08)60469-x. View

Tanaka M, Takei K, Kojima M, Sakakibara H, Mori H . Auxin controls local cytokinin biosynthesis in the nodal stem in apical dominance. Plant J. 2006; 45(6):1028-36. DOI: 10.1111/j.1365-313X.2006.02656.x. View

Beveridge C . Axillary bud outgrowth: sending a message. Curr Opin Plant Biol. 2005; 9(1):35-40. DOI: 10.1016/j.pbi.2005.11.006. View

Booker J, Auldridge M, Wills S, McCarty D, Klee H, Leyser O . MAX3/CCD7 is a carotenoid cleavage dioxygenase required for the synthesis of a novel plant signaling molecule. Curr Biol. 2004; 14(14):1232-8. DOI: 10.1016/j.cub.2004.06.061. View

Abe H, Yamaguchi-Shinozaki K, Urao T, Iwasaki T, Hosokawa D, Shinozaki K . Role of arabidopsis MYC and MYB homologs in drought- and abscisic acid-regulated gene expression. Plant Cell. 1997; 9(10):1859-68. PMC: 157027. DOI: 10.1105/tpc.9.10.1859. View

Booker J, Sieberer T, Wright W, Williamson L, Willett B, Stirnberg P . MAX1 encodes a cytochrome P450 family member that acts downstream of MAX3/4 to produce a carotenoid-derived branch-inhibiting hormone. Dev Cell. 2005; 8(3):443-9. DOI: 10.1016/j.devcel.2005.01.009. View

Morris D . Transport of exogenous auxin in two-branched dwarf pea seedlings (Pisum sativum L.) : Some implications for polarity and apical dominance. Planta. 2014; 136(1):91-6. DOI: 10.1007/BF00387930. View

10.

Stirnberg P, van de Sande K, Leyser H . MAX1 and MAX2 control shoot lateral branching in Arabidopsis. Development. 2002; 129(5):1131-41. DOI: 10.1242/dev.129.5.1131. View

11.

Catterou M, Dubois F, Smets R, Vaniet S, Kichey T, Van Onckelen H . hoc: An Arabidopsis mutant overproducing cytokinins and expressing high in vitro organogenic capacity. Plant J. 2002; 30(3):273-87. DOI: 10.1046/j.1365-313x.2002.01286.x. View

12.

Hall S, Hillman J . Correlative inhibition of lateral bud growth in Phaseolus vulgaris L. timing of bud growth following decapitation. Planta. 2014; 123(2):137-43. DOI: 10.1007/BF00383862. View

13.

Arite T, Umehara M, Ishikawa S, Hanada A, Maekawa M, Yamaguchi S . d14, a strigolactone-insensitive mutant of rice, shows an accelerated outgrowth of tillers. Plant Cell Physiol. 2009; 50(8):1416-24. DOI: 10.1093/pcp/pcp091. View

14.

Dun E, Brewer P, Beveridge C . Strigolactones: discovery of the elusive shoot branching hormone. Trends Plant Sci. 2009; 14(7):364-72. DOI: 10.1016/j.tplants.2009.04.003. View

15.

Stirnberg P, Ward S, Leyser O . Auxin and strigolactones in shoot branching: intimately connected?. Biochem Soc Trans. 2010; 38(2):717-22. DOI: 10.1042/BST0380717. View

16.

Turnbull C, Booker J, Leyser H . Micrografting techniques for testing long-distance signalling in Arabidopsis. Plant J. 2002; 32(2):255-62. DOI: 10.1046/j.1365-313x.2002.01419.x. View

17.

Urao T, Yamaguchi-Shinozaki K, Urao S, Shinozaki K . An Arabidopsis myb homolog is induced by dehydration stress and its gene product binds to the conserved MYB recognition sequence. Plant Cell. 1993; 5(11):1529-39. PMC: 160383. DOI: 10.1105/tpc.5.11.1529. View

18.

Guo Y, Gan S . Leaf senescence: signals, execution, and regulation. Curr Top Dev Biol. 2005; 71:83-112. DOI: 10.1016/S0070-2153(05)71003-6. View

19.

Marumo S, Hattori H, Abe H, Munakata K . Isolation of 4-chloroindolyl-3-acetic acid from immature seeds of Pisum sativum. Nature. 1968; 219(5157):959-60. DOI: 10.1038/219959b0. View

20.

Gan S . Mitotic and postmitotic senescence in plants. Sci Aging Knowledge Environ. 2003; 2003(38):RE7. DOI: 10.1126/sageke.2003.38.re7. View