Live Bird Markets of Bangladesh: H9N2 Viruses and the Near Absence of Highly Pathogenic H5N1 Influenza

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2011 May 5

PMID 21541296

Citations 56

Authors

Nicholas J Negovetich

Mohammed M Feeroz

Lisa Jones-Engel

David Walker

S M Rabiul Alam

Kamrul Hasan

Patrick Seiler

Angie Ferguson

Kim Friedman

Subrata Barman

John Franks

Jasmine Turner

Scott Krauss

Richard J Webby

Robert G Webster

Affiliations

Soon will be listed here.

Abstract

Avian influenza surveillance in Bangladesh has been passive, relying on poultry farmers to report suspected outbreaks of highly pathogenic H5N1 influenza. Here, the results of an active surveillance effort focusing on the live-bird markets are presented. Prevalence of influenza infection in the birds of the live bird markets is 23.0%, which is similar to that in poultry markets in other countries. Nearly all of the isolates (94%) were of the non-pathogenic H9N2 subtype, but viruses of the H1N2, H1N3, H3N6, H4N2, H5N1, and H10N7 subtypes were also observed. The highly pathogenic H5N1-subtype virus was observed at extremely low prevalence in the surveillance samples (0.08%), and we suggest that the current risk of infection for humans in the retail poultry markets in Bangladesh is negligible. However, the high prevalence of the H9 subtype and its potential for interaction with the highly pathogenic H5N1-subtype, i.e., reassortment and attenuation of host morbidity, highlight the importance of active surveillance of the poultry markets.

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