Vitamin D Deficiency and Insulin Resistance in Obese African-American Adolescents

Overview

Journal J Pediatr Endocrinol Metab

Specialties Endocrinology
Pediatrics

Date 2011 May 3

PMID 21528812

Citations 16

Authors

Gail Nunlee-Bland

Kanwal Gambhir

Cynthia Abrams

Mustapha Abdul

Marjan Vahedi

Wolali Odonkor

Affiliations

Soon will be listed here.

Abstract

Objective: The study aim determined if low 25-hydroxy vitamin D levels correlated with low levels of adiponectin and insulin resistance in African American adolescents with body mass index > or = 85th %.

Patients And Methods: Fasting blood levels of adiponectin, 25-hydroxy vitamin D, insulin, glucose, lipid, leptin and glycosylated hemoglobin were measured in a total of 34 (19 study and 15 control) African American adolescents between the ages of 10 and 20 years. Nutritional vitamin D intake and body composition measurements were assessed. Insulin resistance was calculated using the homeostasis model assessment.

Results: Adiponectin, fasting insulin, glucose, leptin, triglycerides, HDL, and 25-hydroxy vitamin D levels all reached statistical significance in the group with body mass index > or = 85th percentile when compared to the control population. There was no difference in vitamin D intake between the two groups.

Conclusions: Low vitamin D levels correlated with low adiponectin levels and obesity and insulin resistance.

Citing Articles

Vitamin D status in children and its association with glucose metabolism in northern China: a combination of a cross-sectional and retrospective study.

Liu J, Fu L, Jin S, Jia Y, Zhang J, Sun C BMJ Open. 2022; 12(11):e061146.

PMID: 36446458 PMC: 9710338. DOI: 10.1136/bmjopen-2022-061146.

Update on the Crosstalk Between Adipose Tissue and Mineral Balance in General Population and Chronic Kidney Disease.

Karava V, Christoforidis A, Kondou A, Dotis J, Printza N Front Pediatr. 2021; 9:696942.

PMID: 34422722 PMC: 8378583. DOI: 10.3389/fped.2021.696942.

Association of Serum 25-Hydroxyvitamin D Level With Metabolic Phenotypes of Obesity in Children and Adolescents: The CASPIAN-V Study.

Esmaili H, Heshmat R, Ejtahed H, Rastad H, Motlagh M, Asayesh H Front Endocrinol (Lausanne). 2020; 11:310.

PMID: 32612573 PMC: 7308554. DOI: 10.3389/fendo.2020.00310.

Vitamin D Supplementation In Obese Africian American Children.

Tangpricha V J Clin Transl Endocrinol. 2018; 12:48-49.

PMID: 29892567 PMC: 5992317. DOI: 10.1016/j.jcte.2018.04.003.

Association of serum vitamin D concentrations with dietary patterns in children and adolescents.

Ganji V, Martineau B, Van Fleit W Nutr J. 2018; 17(1):58.

PMID: 29866150 PMC: 5987485. DOI: 10.1186/s12937-018-0365-7.

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