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Autophagy in Ras-induced Malignant Transformation: Fatal or Vital?

Overview
Journal Mol Cell
Publisher Cell Press
Specialty Cell Biology
Date 2011 Apr 9
PMID 21474062
Citations 11
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Abstract

In this issue of Molecular Cell, Elgendy et al. suggest that Ras-induced autophagy may kill tumor cells on the verge of oncogenic transformation, providing a contrast to recent reports indicating that autophagy is required for optimal growth of Ras-driven cancers.

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