Clusella P, Manubens-Gil L, Garcia-Ojalvo J, Dierssen M
PLoS Comput Biol. 2024; 20(7):e1012259.
PMID: 38968294
PMC: 11253980.
DOI: 10.1371/journal.pcbi.1012259.
Zhakula-Kostadinova N, Taylor A
Cancer Res. 2024; 84(16):2575-2587.
PMID: 38924459
PMC: 11325152.
DOI: 10.1158/0008-5472.CAN-24-0169.
Pereira M, Shyti R, Testa G
Stem Cell Reports. 2024; 19(6):767-795.
PMID: 38865969
PMC: 11390705.
DOI: 10.1016/j.stemcr.2024.05.004.
Chen X, Becker A, Albay R, Nguyen P, Karachentsev D, Roberts A
Ann Neurol. 2024; 96(2):390-404.
PMID: 38747498
PMC: 11236496.
DOI: 10.1002/ana.26958.
Llambrich S, Tielemans B, Salien E, Atzori M, Wouters K, Van Bulck V
Elife. 2024; 12.
PMID: 38497812
PMC: 10948151.
DOI: 10.7554/eLife.89763.
Trisomy 21-driven metabolite alterations are linked to cellular injuries in Down syndrome.
Liu J, Chen S, Huang G, Wen P, Zhou X, Wu Y
Cell Mol Life Sci. 2024; 81(1):112.
PMID: 38433139
PMC: 10909777.
DOI: 10.1007/s00018-024-05127-0.
Breathing and Oxygen Carrying Capacity in Ts65Dn and Down Syndrome.
DeRuisseau L, Receno C, Cunningham C, Bates M, Goodell M, Liang C
Function (Oxf). 2023; 4(6):zqad058.
PMID: 37954975
PMC: 10634617.
DOI: 10.1093/function/zqad058.
Maternal choline supplementation protects against age-associated cholinergic and GABAergic basal forebrain neuron degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.
Gautier M, Kelley C, Lee S, Alldred M, McDaid J, Mufson E
Neurobiol Dis. 2023; 188:106332.
PMID: 37890559
PMC: 10752300.
DOI: 10.1016/j.nbd.2023.106332.
Glutamatergic synaptic deficits in the prefrontal cortex of the Ts65Dn mouse model for Down syndrome.
Thomazeau A, Lassalle O, Manzoni O
Front Neurosci. 2023; 17:1171797.
PMID: 37841687
PMC: 10569174.
DOI: 10.3389/fnins.2023.1171797.
Understanding the genetic mechanisms and cognitive impairments in Down syndrome: towards a holistic approach.
Abukhaled Y, Hatab K, Awadhalla M, Hamdan H
J Neurol. 2023; 271(1):87-104.
PMID: 37561187
PMC: 10769995.
DOI: 10.1007/s00415-023-11890-0.
Modeling Alzheimer's disease related phenotypes in the Ts65Dn mouse: impact of age on Aβ, Tau, pTau, NfL, and behavior.
Overk C, Fiorini E, Babolin C, Vukicevic M, Morici C, Madani R
Front Neurosci. 2023; 17:1202208.
PMID: 37449271
PMC: 10336548.
DOI: 10.3389/fnins.2023.1202208.
Emergence of Treadmill Running Ability and Quantitative Assessment of Gait Dynamics in Young Ts65Dn Mice: A Mouse Model for Down Syndrome.
Scott-McKean J, Jones R, Johnson M, Mier J, Basten I, Stasko M
Brain Sci. 2023; 13(5).
PMID: 37239215
PMC: 10216633.
DOI: 10.3390/brainsci13050743.
The Impact of Mmu17 Non-Hsa21 Orthologous Genes in the Ts65Dn Mouse Model of Down Syndrome: The Gold Standard Refuted.
Guedj F, Kane E, Bishop L, Pennings J, Herault Y, Bianchi D
Biol Psychiatry. 2023; 94(1):84-97.
PMID: 37074246
PMC: 10330375.
DOI: 10.1016/j.biopsych.2023.02.012.
Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome.
Xing Z, Li Y, Cortes-Gomez E, Jiang X, Gao S, Pao A
Hum Mol Genet. 2023; 32(13):2205-2218.
PMID: 37014740
PMC: 10281752.
DOI: 10.1093/hmg/ddad056.
Overexpression screen of chromosome 21 genes reveals modulators of Sonic hedgehog signaling relevant to Down syndrome.
Moyer A, Fernandez F, Li Y, Klinedinst D, Florea L, Kazuki Y
Dis Model Mech. 2023; 16(4).
PMID: 36995257
PMC: 10120076.
DOI: 10.1242/dmm.049712.
Dysregulated systemic metabolism in a Down syndrome mouse model.
Sarver D, Xu C, Velez L, Aja S, Jaffe A, Seldin M
Mol Metab. 2023; 68:101666.
PMID: 36587842
PMC: 9841171.
DOI: 10.1016/j.molmet.2022.101666.
GIRK2 Channels in Down Syndrome and Alzheimer's Disease.
Kleschevnikov A
Curr Alzheimer Res. 2022; 19(12):819-829.
PMID: 36567290
DOI: 10.2174/1567205020666221223122110.
Ts66Yah, a mouse model of Down syndrome with improved construct and face validity.
Duchon A, Muniz Moreno M, Chevalier C, Nalesso V, Andre P, Fructuoso-Castellar M
Dis Model Mech. 2022; 15(12).
PMID: 36374158
PMC: 9789398.
DOI: 10.1242/dmm.049721.
Aβ and tau prions feature in the neuropathogenesis of Down syndrome.
Condello C, Maxwell A, Castillo E, Aoyagi A, Graff C, Ingelsson M
Proc Natl Acad Sci U S A. 2022; 119(46):e2212954119.
PMID: 36343257
PMC: 9674250.
DOI: 10.1073/pnas.2212954119.
From gene editing to genome engineering: restructuring plant chromosomes via CRISPR/Cas.
Schmidt C, Schindele P, Puchta H
aBIOTECH. 2022; 1(1):21-31.
PMID: 36305002
PMC: 9584095.
DOI: 10.1007/s42994-019-00002-0.