Diarrheagenic Pathogens in Polymicrobial Infections

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2011 Apr 8

PMID 21470448

Citations 18

Authors

Brianna Lindsay

T Ramamurthy

Sourav Sen Gupta

Yoshifumi Takeda

Krishnan Rajendran

G Balakrish Nair

O Colin Stine

Affiliations

Soon will be listed here.

Abstract

During systematic active surveillance of the causes of diarrhea in patients admitted to the Infectious Diseases and Beliaghata General Hospital in Kolkata, India, we looked for 26 known gastrointestinal pathogens in fecal samples from 2,748 patients. Samples from about one-third (29%) of the patients contained multiple pathogens. Polymicrobial infections frequently contained Vibrio cholerae O1 and rotavirus. When these agents were present, some co-infecting agents were found significantly less often (p = 10 (-5) to 10 (-33), some were detected significantly more often (p = 10 (-5) to 10 (-26), and others were detected equally as often as when V. cholerae O1 or rotavirus was absent. When data were stratified by patient age and season, many nonrandom associations remained statistically significant. The causes and effects of these nonrandom associations remain unknown.

Citing Articles

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Detection of Foodborne Pathogens in Acute Gastroenteritis Patient's Stool Samples Using the BioFire FilmArray Gastrointestinal PCR Panel in the Republic of Trinidad and Tobago, West Indies.

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Viral and Bacterial Co-Infection and Its Implications.

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Coinfection with Enteric Pathogens in East African Children with Acute Gastroenteritis-Associations and Interpretations.

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