MicroRNA History: Discovery, Recent Applications, and Next Frontiers

Overview

Journal Mutat Res

Publisher Elsevier

Specialty Genetics

Date 2011 Apr 5

PMID 21458467

Citations 172

Authors

Maria I Almeida

Rui M Reis

George A Calin

Affiliations

Soon will be listed here.

Abstract

Since 1993, when the first small non-coding RNA was identified, our knowledge about microRNAs has grown exponentially. In this review, we focus on the main progress in this field and discuss the most important findings under a historical perspective. In addition, we examine microRNAs as markers of disease diagnosis and prognosis, and as new therapeutic targets.

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