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Hyaluronic Acid Dermal Fillers: Can Adjunctive Lidocaine Improve Patient Satisfaction Without Decreasing Efficacy or Duration?

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Date 2011 Mar 31
PMID 21448297
Citations 20
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Abstract

Hyaluronic acid (HA) dermal fillers are the most widely used injectables to augment facial volume without surgery. HA dermal fillers are popular because of their ease of administration, predictable effectiveness, good safety profile, and quick patient recovery. The most common patient complaint is pain. Our goal is to review the current literature on HA fillers and compare outcomes with and without lidocaine. We found adjunctive lidocaine significantly decreases pain during injection and postinjection with corresponding increased patient satisfaction. The efficacy and safety profile appears unchanged. Rare complications with HA fillers and those associated with constituents of the product, contaminants, and lidocaine are reviewed. The corrective effects of HA fillers are temporary; repeat treatment is required to maintain results. Minimizing pain is crucial to optimize patient satisfaction.

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References
1.
Librowski T, Pytka K, Szaleniec M . Antihistaminic activity of carane derivatives in isolated guinea pig ileum. Pharmacol Rep. 2010; 61(6):1211-5. DOI: 10.1016/s1734-1140(09)70186-0. View

2.
Levy P, De Boulle K, Raspaldo H . Comparison of injection comfort of a new category of cohesive hyaluronic acid filler with preincorporated lidocaine and a hyaluronic acid filler alone. Dermatol Surg. 2009; 35 Suppl 1:332-6. DOI: 10.1111/j.1524-4725.2008.01045.x. View

3.
Alijotas-Reig J, Garcia-Gimenez V . Delayed immune-mediated adverse effects related to hyaluronic acid and acrylic hydrogel dermal fillers: clinical findings, long-term follow-up and review of the literature. J Eur Acad Dermatol Venereol. 2008; 22(2):150-61. DOI: 10.1111/j.1468-3083.2007.02354.x. View

4.
Rohrich R, Herbig K . Minimizing pain, maximizing comfort: a new technique for facial filler injections. Plast Reconstr Surg. 2009; 124(4):1328-1329. DOI: 10.1097/PRS.0b013e3181b458ea. View

5.
Custis T, Beynet D, Carranza D, Greco J, Lask G, Kim J . Comparison of treatment of melomental fold rhytides with cross-linked hyaluronic acid combined with onabotulinumtoxina and cross-linked hyaluronic acid alone. Dermatol Surg. 2010; 36 Suppl 3:1852-8. DOI: 10.1111/j.1524-4725.2010.01741.x. View