Case Report: Pulmonary Syphilis Mimicking Pulmonary Hematogenous Metastases on Chest CT and Integrated PET/CT
Overview
Affiliations
We report a case of syphilis with pulmonary involvement. Chest CT scan and (18)F-fluorodeoxyglucose (FDG) PET/CT showed multiple pulmonary nodules mimicking pulmonary hematogenous metastases. This was confirmed on follow-up images that showed therapeutic response to penicillin.
Syphilitic pneumonia: case report and systematic review.
Pipitone G, Abbott M, Gizzi A, Buscemi C, Guida Marascia F, Imburgia C Infez Med. 2025; 33(1):130-138.
PMID: 40071253 PMC: 11892446. DOI: 10.53854/liim-3301-13.
An Unusual Case of Syphilis With Pulmonary Involvement.
Arzoun H, Mohammed F, Saeed S, Khan T, Singh K Cureus. 2024; 16(7):e63758.
PMID: 39100049 PMC: 11296560. DOI: 10.7759/cureus.63758.
Pulmonary infection masquerades as malignancy in a patient with periodontitis.
Turner E, Hastie T, Sundaresan P BMJ Case Rep. 2021; 14(2).
PMID: 33526536 PMC: 7852944. DOI: 10.1136/bcr-2020-239636.
Chen J, Zheng X, Liu X Chin Med J (Engl). 2017; 130(9):1100-1112.
PMID: 28469107 PMC: 5421182. DOI: 10.4103/0366-6999.204940.
Unusual presentations and pitfalls of secondary syphilis: osteitis, pneumonia and malignancy.
Crouzy F, Alvarez V, Gex G, Troillet N BMJ Case Rep. 2015; 2015.
PMID: 26504092 PMC: 4636704. DOI: 10.1136/bcr-2015-210618.