Dietary Flavonoids As Cancer Prevention Agents

Overview

Journal J Environ Sci Health C Environ Carcinog Ecotoxicol Rev

Specialties Environmental Health
Toxicology

Date 2011 Mar 23

PMID 21424974

Citations 34

Authors

Hua Yao

Weizheng Xu

Xianglin Shi

Zhuo Zhang

Affiliations

Soon will be listed here.

Abstract

Dietary agents identified from fruits and vegetables contribute to keeping balanced cell proliferation and preventing cell carcinogenesis. Dietary flavonoids, combined with other components such as various vitamins, play an important role in cancer prevention. Flavonoids act on reactive oxygen species, cell signal transduction pathways related to cellular proliferation, apoptosis, and angiogenesis. Many studies demonstrate that flavonoids are responsible for chemoprevention, although mechanisms of action remain to be investigated. Overall, exciting data show that dietary flavonoids could be considered as a useful cancer preventive approach. This review summarizes recent advancements on potential cancer preventive effects and mechanic insight of dietary flavonoids.

Citing Articles

The influence of dietary vegetables and fruits on endometrial cancer risk: a meta-analysis of observational studies.

Lu Y, Gunathilake M, Kim J Eur J Clin Nutr. 2022; 77(5):561-573.

PMID: 36151331 DOI: 10.1038/s41430-022-01213-3.

Pomegranate seed extract enhances the inhibitory effect of adipose-derived mesenchymal stem cells on breast cancer cell line in co-culture conditions.

Moradi-Gharibvand N, Setayeshmehr M, Kazemi M, Safaee A, Khorsandi L, Bijan Nejad D Res Pharm Sci. 2022; 17(4):372-382.

PMID: 36034084 PMC: 9400461. DOI: 10.4103/1735-5362.350238.

Cytotoxic Activity of Polyphenol Extracts from Three Oregano Species: , and and Antiproliferative Potential of against Two Types of Breast Cancer Cell Lines (MDA-MB-231 and MCF-7).

Criollo-Mendoza M, Ramos-Payan R, Contreras-Angulo L, Gutierrez-Grijalva E, Leon-Felix J, Villicana C Molecules. 2022; 27(16).

PMID: 36014479 PMC: 9415836. DOI: 10.3390/molecules27165240.

Quercetin Can Inhibit Angiogenesis via the Down Regulation of MALAT1 and MIAT LncRNAs in Human Umbilical Vein Endothelial Cells.

Esteghlal S, Mokhtari M, Beyzaei Z Int J Prev Med. 2021; 12:59.

PMID: 34447501 PMC: 8356977. DOI: 10.4103/ijpvm.IJPVM_103_20.

Chemical characterization and in vitro immunomodulatory effects of different extracts of moss Hedwigia ciliata (Hedw.) P. Beauv. from the Vršačke Planine Mts., Serbia.

Mandic M, Oalde M, Lunic T, Sabovljevic A, Sabovljevic M, Gasic U PLoS One. 2021; 16(2):e0246810.

PMID: 33571277 PMC: 7877662. DOI: 10.1371/journal.pone.0246810.