» Articles » PMID: 21410958

Safety of Pull-type and Introducer Percutaneous Endoscopic Gastrostomy Tubes in Oncology Patients: a Retrospective Analysis

Overview
Publisher Biomed Central
Specialty Gastroenterology
Date 2011 Mar 18
PMID 21410958
Citations 16
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Percutaneous endoscopic gastrostomy (PEG) allows long-term tube feeding. Safety of pull-type and introducer PEG placement in oncology patients with head/neck or oesophageal malignancies is unknown.

Methods: Retrospective analysis of 299 patients undergoing PEG tube placement between January 2006 and December 2008 revealed 57 oncology patients. All patients with head/neck or oesophageal malignancy were treated with chemo- and radiotherapy. In case of high-grade stenosis introducer Freka® Pexact PEG tube was placed (n = 24) and in all other patients (n = 33) conventional pull-type PEG tube. Short-term complications and mortality rates were compared.

Results: Patients' characteristics and clinical status were comparable in both groups. Short-term complications were encountered in 11/24 (48%) introducer PEG patients as compared to only 4/33 (12%) pull-type PEG patients (P < 0.05). Accidental removal of the introducer PEG tube occurred in 4/24 (17%) with need for surgical intervention in 1 vs. 0/33 (0%, P < 0.05). Wound infection occurred in 3/24 (12%) leading to septic shock and admission to intensive care unit (ICU) in 1 vs. 3/33 (9%, NS). Finally, 3/24 gastrointestinal perforations (12%) resulted from a difficult placement procedure vs. 1/33 (3%), leading to urgent surgical intervention and admission to ICU. Two introducer PEG patients died at ICU, resulting in an overall mortality rate of 8% vs. 0% (P = 0.091).

Conclusion: The introducer Freka® Pexact PEG procedure for long-term tube feeding may lead to significantly higher complication and mortality rates in patients with head/neck or oesophageal malignancies treated with chemo- and radiotherapy. It is suggested to use the conventional pull-type PEG tube placement in this group of patients, if possible.

Citing Articles

Hybrid percutaneous endoscopic gastrostomy (Hybrid PEG) improves patient safety by combining pull-through technique with gastropexy.

Kinzel T, Reich V, Schuhmacher L, Bojarski C, Adler A, Veltzke-Schlieker W Endosc Int Open. 2025; 13:a25112096.

PMID: 40018077 PMC: 11866035. DOI: 10.1055/a-2511-2096.


Percutaneous Gastrostomies: Associated Complications in PUSH vs. PULL Techniques over 12 Years in a Referral Centre.

Pinar-Gutierrez A, Gonzalez-Gracia L, Vazquez Gutierrez R, Garcia-Rey S, Jimenez-Sanchez A, Gonzalez-Navarro I J Clin Med. 2024; 13(7).

PMID: 38610601 PMC: 11012573. DOI: 10.3390/jcm13071836.


Clinical Practice Guideline for Percutaneous Endoscopic Gastrostomy.

Tae C, Lee J, Joo M, Park C, Gong E, Shin C Gut Liver. 2023; 18(1):10-26.

PMID: 37850251 PMC: 10791499. DOI: 10.5009/gnl230146.


Clinical practice guidelines for percutaneous endoscopic gastrostomy.

Tae C, Lee J, Joo M, Park C, Gong E, Shin C Clin Endosc. 2023; 56(4):391-408.

PMID: 37430395 PMC: 10393568. DOI: 10.5946/ce.2023.062.


Effectiveness of betadine-coating gastrostomy tube to reduce peristomal infection after percutaneous endoscopic gastrostomy: a randomized controlled trial.

Chen Y, Hou M, Yang T, Lee P, Wang Y, Huang Y BMC Gastroenterol. 2023; 23(1):155.

PMID: 37189057 PMC: 10186665. DOI: 10.1186/s12876-023-02702-w.


References
1.
Cosentini E, Sautner T, Gnant M, Winkelbauer F, Teleky B, Jakesz R . Outcomes of surgical, percutaneous endoscopic, and percutaneous radiologic gastrostomies. Arch Surg. 1998; 133(10):1076-83. DOI: 10.1001/archsurg.133.10.1076. View

2.
Oken M, Creech R, Tormey D, Horton J, Davis T, McFadden E . Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982; 5(6):649-55. View

3.
Grant D, Bradley P, Pothier D, Bailey D, Caldera S, Baldwin D . Complications following gastrostomy tube insertion in patients with head and neck cancer: a prospective multi-institution study, systematic review and meta-analysis. Clin Otolaryngol. 2009; 34(2):103-12. DOI: 10.1111/j.1749-4486.2009.01889.x. View

4.
Dormann A, Wejda B, Kahl S, Huchzermeyer H, Ebert M, Malfertheiner P . Long-term results with a new introducer method with gastropexy for percutaneous endoscopic gastrostomy. Am J Gastroenterol. 2006; 101(6):1229-34. DOI: 10.1111/j.1572-0241.2006.00541.x. View

5.
Baltz J, Argo C, Al-Osaimi A, Northup P . Mortality after percutaneous endoscopic gastrostomy in patients with cirrhosis: a case series. Gastrointest Endosc. 2010; 72(5):1072-5. DOI: 10.1016/j.gie.2010.06.043. View