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Reversible Retinal Edema in an Infant with Neonatal Hemochromatosis and Liver Failure

Overview
Journal J AAPOS
Specialty Pediatrics
Date 2011 Mar 15
PMID 21397814
Citations 14
Authors
Ramiro S Maldonado
Sharon F Freedman
C Michael Cotten
Jeffrey M Ferranti
Cynthia A Toth
Affiliations
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Abstract

We present a case of bilateral severe retinal edema with subretinal fluid in an infant diagnosed with neonatal hemochromatosis and liver failure. A macular cherry-red spot in each eye mimicked the clinical appearance of many metabolic storage diseases. Both the clinical retinal appearance and the anatomic abnormalities observed on spectral domain optical coherence tomography resolved after successful liver transplant.

Citing Articles

Preterm infant retinal OCT markers of perinatal health and retinopathy of prematurity.

Mangalesh S, Toth C Front Pediatr. 2023; 11:1238193.

PMID: 37808559 PMC: 10551634. DOI: 10.3389/fped.2023.1238193.

Morphological characteristics of early- versus late-onset macular edema in preterm infants.

Mangalesh S, Wong B, Chen X, Tran-Viet D, Stinnett S, Sarin N J AAPOS. 2020; 24(5):303-306.

PMID: 32942022 PMC: 8006576. DOI: 10.1016/j.jaapos.2020.06.006.

Fluorescein Angiographic Characteristics of Macular Edema During Infancy.

Chen X, Mangalesh S, Tran-Viet D, Freedman S, Vajzovic L, Toth C JAMA Ophthalmol. 2018; 136(5):538-542.

PMID: 29621379 PMC: 6145655. DOI: 10.1001/jamaophthalmol.2018.0467.

Optical coherence tomography of the preterm eye: from retinopathy of prematurity to brain development.

Rothman A, Mangalesh S, Chen X, Toth C Eye Brain. 2017; 8:123-133.

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Retinal Imaging of Infants on Spectral Domain Optical Coherence Tomography.

Vinekar A, Mangalesh S, Jayadev C, Maldonado R, Bauer N, Toth C Biomed Res Int. 2015; 2015:782420.

PMID: 26221606 PMC: 4506845. DOI: 10.1155/2015/782420.

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