Pulmonary Epithelioid Hemangioendothelioma with PlGF Expression: Report of a Case

Overview

Journal Thorac Cardiovasc Surg

Date 2011 Mar 9

PMID 21384313

Citations 4

Authors

T Haruki

T Arai

H Nakamura

K Nosaka

K Shomori

H Ito

Affiliations

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Abstract

Pulmonary epithelioid hemangioendothelioma (PEH) is a relatively uncommon neoplasm of vascular origin with a low or intermediate grade of malignancy. We present a case of a 28-year-old female with multiple pulmonary nodules which were diagnosed as PEH by video-assisted thoracoscopic surgery (VATS) biopsy. In addition, we performed an immunohistochemical analysis for placenta growth factor (PlGF) and a strong positivity for PlGF observed, suggesting that the PlGF may play some role in the tumorigenesis of PEH.

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