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A Zero- and K-inflated Mixture Model for Health Questionnaire Data

Overview
Journal Stat Med
Publisher Wiley
Specialty Public Health
Date 2011 Mar 3
PMID 21365673
Citations 11
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Abstract

In psychiatric assessment, Item Response Theory (IRT) is a popular tool to formalize the relation between the severity of a disorder and the associated responses to questionnaire items. Practitioners of IRT sometimes make the assumption of normally distributed severities within a population; while convenient, this assumption is often violated when measuring psychiatric disorders. Specifically, there may be a sizable group of respondents whose answers place them at an extreme of the latent trait spectrum. In this article, a zero- and K-inflated mixture model is developed to account for the presence of such respondents. The model is fitted using an expectation-maximization (E-M) algorithm to estimate the percentage of the population at each end of the continuum, concurrently analyzing the remaining 'graded component' via IRT. A method to perform factor analysis for only the graded component is introduced. In assessments of oppositional defiant disorder and conduct disorder, the zero- and K-inflated model exhibited better fit than the standard IRT model.

Citing Articles

Item Response Modeling of Clinical Instruments With Filter Questions: Disentangling Symptom Presence and Severity.

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Symptom Presence and Symptom Severity as Unique Indicators of Psychopathology: An Application of Multidimensional Zero-Inflated and Hurdle Graded Response Models.

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DIF Detection With Zero-Inflation Under the Factor Mixture Modeling Framework.

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Matching IRT Models to Patient-Reported Outcomes Constructs: The Graded Response and Log-Logistic Models for Scaling Depression.

Reise S, Du H, Wong E, Hubbard A, Haviland M Psychometrika. 2021; 86(3):800-824.

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A study of alternative approaches to non-normal latent trait distributions in item response theory models used for health outcome measurement.

Smits N, Ogreden O, Garnier-Villarreal M, Terwee C, Chalmers R Stat Methods Med Res. 2020; 29(4):1030-1048.

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