Pneumococcal Peritonitis: Still with Us and Likely to Increase in Importance

Overview

Journal Can J Infect Dis Med Microbiol

Publisher Wiley

Date 2011 Mar 2

PMID 21358876

Citations 7

Authors

Darcy C Waisman

Gregory J Tyrrell

James D Kellner

Sipi Garg

Thomas J Marrie

Affiliations

Soon will be listed here.

Abstract

Background: Pneumococcal peritonitis is uncommon and poorly understood.

Methods: As part of a five-year study (2000 to 2004) of invasive pneumococcal disease (IPD) in Alberta, all cases of peritonitis due to Streptococcus pneumoniae were reviewed and compared with all other cases of IPD.

Results: Twenty-three of 1768 (1.3%) IPD patients were found to have peritonitis. Patients with peritonitis were more likely to have cirrhosis, hepatitis C, alcoholism and HIV/AIDS, than the remainder of the patients with IPD. The all-cause mortality did not differ between the two groups. Peritonitis was classified as primary in nine (39%) patients, secondary in 12 (52%) patients, and genitourinary in females, specifically, in two (9%) patients. Pneumococcal serotypes causing peritonitis were under-represented in current vaccines - 17% among peritonitis patients versus 53% for the remainder of IPD patients for the 7-valent pneumococcal conjugate vaccine, and 56% versus 86% for the 23-valent pneumococcal polysaccharide vaccine.

Conclusions: Peritonitis represents a small subset of patients with IPD, but one that is likely to grow in importance given the increase in the number of patients with hepatitis C and HIV, and the reduced coverage of peritonitis serotypes in currently available vaccines.

Citing Articles

Intrafamilial Transmission of Pneumococcal Acute Spontaneous Peritonitis.

Papadatou I, Moudaki A, Mentessidou A, Tsakogiannis D, Georgiadou E, Spoulou V Infect Dis Rep. 2023; 15(3):299-306.

PMID: 37367189 PMC: 10297942. DOI: 10.3390/idr15030030.

Primary Bacterial Peritonitis Caused by .

Maraki S, Moraitis P, Barbagadakis S, Vlachakis I J Glob Infect Dis. 2021; 13(2):103-104.

PMID: 34194180 PMC: 8213084. DOI: 10.4103/jgid.jgid_197_20.

Primary pneumococcal peritonitis can be the first presentation of a familial complement factor I deficiency.

Ugrinovic S, Firth H, Kavanagh D, Gouliouris T, Gurugama P, Baxendale H Clin Exp Immunol. 2020; 202(3):379-383.

PMID: 32640035 PMC: 7670128. DOI: 10.1111/cei.13490.

Pneumococcal perihepatitis due to hematogeneous dissemination.

Okumura K, Sato Y, Yonekura H, Toki N, Kuki T, Watanuki S IDCases. 2020; 21:e00856.

PMID: 32518756 PMC: 7272505. DOI: 10.1016/j.idcr.2020.e00856.

Spontaneous pneumococcal peritonitis diagnosed by qPCR.

Jarovsky D, Grodzicki Ambrus T, Galvao Gurgel M, Mimica M, Volpe Arnoni M, Almeida F IDCases. 2019; 15:e00489.

PMID: 30656139 PMC: 6327877. DOI: 10.1016/j.idcr.2019.e00489.

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