Diversity-oriented Approach to Pyrrole-imidazole Alkaloid Frameworks

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2011 Feb 23

PMID 21338082

Citations 1

Authors

Manojkumar R Bhandari

Muhammed Yousufuddin

Carl J Lovely

Affiliations

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Abstract

An exploration of imidazolylpropargyl amides as linchpin synthons for the construction of a diverse array of heterocyclic frameworks, many of which are related to those found in the oroidin derived alkaloids, is described. One such intermediate has been used in a formal total synthesis of cyclooroidin.

Citing Articles

Preparation and Diels-Alder reactions of 1'-heterosubsituted vinylimidazoles.

Ray A, Mukherjee S, Das J, Bhandari M, Du H, Yousufuddin M Tetrahedron Lett. 2015; 56(23):3518-3522.

PMID: 26139945 PMC: 4484863. DOI: 10.1016/j.tetlet.2015.01.190.

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