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A Comparison of the Effectiveness Between Amniotic Membrane Homogenate and Transplanted Amniotic Membrane in Healing Corneal Damage in a Rabbit Model

Overview
Journal Acta Ophthalmol
Specialty Ophthalmology
Date 2011 Feb 12
PMID 21310014
Citations 20
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Abstract

Purpose: To determine whether amniotic membrane homogenate is as effective in healing corneal damage as amniotic membrane transplantation in a rabbit model.

Method: The rabbits were divided into three groups. The cornea of one eye in each rabbit was incised resulting in a defect of approximately 8 mm in diameter. Amniotic membrane transplantation was performed in the first group, and amnion homogenate was administered four times a day in the second group. The third group was the control group.

Results: There were no differences in the diameter of the defects and the rate of corneal growth between the amnion transplant group and the amnion homogenate group.

Conclusion: Amnion homogenate is as effective as transplanted amniotic membrane in promoting corneal healing in a rabbit model.

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