Viruses and Asthma

Overview

Journal Biochim Biophys Acta

Specialties Biochemistry
Biophysics

Date 2011 Feb 5

PMID 21291960

Citations 29

Authors

Daniel E Dulek

R Stokes Peebles Jr

Affiliations

Soon will be listed here.

Abstract

Background: Viral respiratory infection has long been known to influence the occurrence of asthma exacerbations. Over the last 20years much effort has been put into clarifying the role that viral respiratory infections play in the eventual development of asthma.

Scope Of Review: In this review we give a general background of the role of viruses in the processes of asthma exacerbation and asthma induction. We review recent additions to the literature in the last 3years with particular focus on clinical and epidemiologic investigations of influenza, rhinovirus, bocavirus, respiratory syncytial virus, and metapneumovirus.

Major Conclusions: The development of asthma emerges from a complex interaction of genetic predisposition and environmental factors with viral infection likely playing a significant role in the effect of environment on asthma inception. This article is part of a Special Issue entitled: Biochemistry of Asthma.

General Significance: Further understanding of the role that viruses play in asthma exacerbation and inception will contribute to decreased asthma morbidity in the future. This article is part of a Special Issue entitled: Biochemistry of Asthma.

Citing Articles

Indoor bioaerosols and asthma: Overview, implications, and mitigation strategies.

Dannemiller K, Conrad L, Haines S, Huang Y, Marr L, Siegel J J Allergy Clin Immunol. 2024; 155(3):714-725.

PMID: 39613110 PMC: 11875944. DOI: 10.1016/j.jaci.2024.11.027.

Respiratory Syncytial Virus Infection in Older Adults: An Update.

Alfano F, Bigoni T, Caggiano F, Papi A Drugs Aging. 2024; 41(6):487-505.

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Safety of Live Attenuated Influenza Vaccine in Children With Asthma.

Sokolow A, Stallings A, Kercsmar C, Harrington T, Jimenez-Truque N, Zhu Y Pediatrics. 2022; 149(4).

PMID: 35342923 PMC: 11235090. DOI: 10.1542/peds.2021-055432.

Identification and seasonality of rhinovirus and respiratory syncytial virus in asthmatic children in tropical climate.

Lopes G, Amorim I, de Oliveira de Melo B, Maramaldo C, Bomfim M, Neto L Biosci Rep. 2020; 40(9).

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Cancer; an induced disease of twentieth century! Induction of tolerance, increased entropy and 'Dark Energy': loss of biorhythms (Anabolism v. Catabolism).

Khatami M Clin Transl Med. 2018; 7(1):20.

PMID: 29961900 PMC: 6026585. DOI: 10.1186/s40169-018-0193-6.

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