» Articles » PMID: 21281704

Phytocomplexes from Liquorice (Glycyrrhiza Glabra L.) Leaves--chemical Characterization and Evaluation of Their Antioxidant, Anti-genotoxic and Anti-inflammatory Activity

Overview
Journal Fitoterapia
Publisher Elsevier
Date 2011 Feb 2
PMID 21281704
Citations 28
Authors
Affiliations
Soon will be listed here.
Abstract

Three extracts of different polarities of Glycyrrhiza glabra L. leaves were characterized and evaluated for their antioxidant, anti-genotoxic and anti-inflammatory activity. In total, thirty components have been identified and quantified through the use of liquid chromatography (LC) with ultraviolet-visible diode-array-detector (UV-vis-DAD) and mass spectrometry (MS). The main components belong to the polyphenols family, being flavonoid and dihydrostilbene derivatives. The extracts have been investigated for their antioxidant, anti-genotoxic and anti-inflammatory activities, which are fundamental requirements of efficacious chemo-preventive agents. The ethyl acetate extract proved to be the most valuable, evidently for the conspicuous presence of several polyphenols, namely flavonoids and dihydrostilbenes.

Citing Articles

Exploiting L. (Licorice) Flavanones: Licoflavanone's Impact on Breast Cancer Cell Bioenergetics.

Frattaruolo L, Lauria G, Aiello F, Carullo G, Curcio R, Fiorillo M Int J Mol Sci. 2024; 25(14).

PMID: 39063149 PMC: 11276871. DOI: 10.3390/ijms25147907.


Exploring Influence of Production Area and Harvest Time on Specialized Metabolite Content of Leaves and Evaluation of Antioxidant and Anti-Aging Properties.

Docimo T, Celano R, Lambiase A, Di Sanzo R, Serio S, Santoro V Antioxidants (Basel). 2024; 13(1).

PMID: 38247517 PMC: 10812728. DOI: 10.3390/antiox13010093.


A review of the bioactive properties of Mongolian plants, with a focus on their potential as natural food preservatives.

Burenjargal M, Narangerel T, Batmunkh T, Dong A, Idesh S Food Sci Nutr. 2023; 11(10):5736-5752.

PMID: 37823130 PMC: 10563759. DOI: 10.1002/fsn3.3529.


Liquorice Toxicity: A Comprehensive Narrative Review.

Ceccuzzi G, Rapino A, Perna B, Costanzini A, Farinelli A, Fiorica I Nutrients. 2023; 15(18).

PMID: 37764649 PMC: 10537237. DOI: 10.3390/nu15183866.


Progress in the mechanism of autophagy and traditional Chinese medicine herb involved in alcohol-related liver disease.

Han W, Li H, Jiang H, Xu H, Lin Y, Chen J PeerJ. 2023; 11:e15977.

PMID: 37727691 PMC: 10506582. DOI: 10.7717/peerj.15977.