Principles of and Advances in Percutaneous Ablation

Overview

Journal Radiology

Specialty Radiology

Date 2011 Jan 29

PMID 21273519

Citations 280

Authors

Muneeb Ahmed

Christopher L Brace

Fred T Lee Jr

S Nahum Goldberg

Affiliations

Soon will be listed here.

Abstract

Image-guided tumor ablation with both thermal and nonthermal sources has received substantial attention for the treatment of many focal malignancies. Increasing interest has been accompanied by continual advances in energy delivery, application technique, and therapeutic combinations with the intent to improve the efficacy and/or specificity of ablative therapies. This review outlines clinical percutaneous tumor ablation technology, detailing the science, devices, techniques, technical obstacles, current trends, and future goals in percutaneous tumor ablation. Methods such as chemical ablation, cryoablation, high-temperature ablation (radiofrequency, microwave, laser, and ultrasound), and irreversible electroporation will be discussed. Advances in technique will also be covered, including combination therapies, tissue property modulation, and the role of computer modeling for treatment optimization.

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