Ritonavir-induced Acute Kidney Injury: Kidney Biopsy Findings and Review of Literature
Overview
Affiliations
Ritonavir therapy is not generally considered nephrotoxic. We report a case of acute kidney injury secondary to ritonavir, with kidney biopsy demonstrating extensive acute tubular injury. This is the first report of a kidney biopsy and pathology in acute kidney injury associated with ritonavir. A review of published medical literature on the topic is also presented.
The Potential of to Ameliorate the Adverse Effects of Highly Active Antiretroviral Therapy (HAART).
Sibiya T, Ghazi T, Chuturgoon A Nutrients. 2022; 14(15).
PMID: 35893930 PMC: 9332774. DOI: 10.3390/nu14153076.
Grimaldi D, Aissaoui N, Blonz G, Carbutti G, Courcelle R, Gaudry S Ann Intensive Care. 2020; 10(1):131.
PMID: 33025225 PMC: 7537971. DOI: 10.1186/s13613-020-00751-y.
Laurence J, Elhadad S, Gostynska S, Yu Z, Terry H, Varshney R AIDS. 2020; 34(7):989-1000.
PMID: 32167970 PMC: 7210074. DOI: 10.1097/QAD.0000000000002516.
Renal stone composed of ritonavir.
Zhao A, Angoff N BMJ Case Rep. 2019; 12(7).
PMID: 31266762 PMC: 6605930. DOI: 10.1136/bcr-2019-230487.
Approach to acute kidney injury in HIV-infected patients in South Africa.
Boswell M, Rossouw T South Afr J HIV Med. 2018; 18(1):714.
PMID: 29568636 PMC: 5843257. DOI: 10.4102/sajhivmed.v18i1.714.