Sentinel Node Biopsy for Breast Cancer Patients: Issues for Discussion and Our Practice

Overview

Journal Patholog Res Int

Publisher Hindawi

Specialty Pathology

Date 2011 Jan 15

PMID 21234361

Authors

Georgios Pechlivanides

Dorothy Vassilaros

Anastasios Tsimpanis

Anastasia Apostolopoulou

Stamatis Vasilaros

Affiliations

Soon will be listed here.

Abstract

Sentinel node biopsy has been established for several years now as a standard procedure of breast cancer surgery, but there are several variations of the indications and the technique used. This paper provides information regarding several issues of debate for its application as are the selection criteria, the application to patients with multifocal/multicentric breast cancer or DCIS, postneoadjuvant chemotherapy, the necessary number of nodes to be biopsied, the need for lymphoscintigraphy, the technique for frozen section, the factors that may predict nonsentinel nodes (NSNs) involvement, the value of micrometastasis and isolated tumour cells, the internal mammary chain sentinel nodes, and finally the axillary recurrence after SLNB. Our view for these issues is included together with our experience of 430 SLNBs.

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