Endodontic Microbiology

Overview

Journal J Conserv Dent

Specialty Dentistry

Date 2011 Jan 11

PMID 21217951

Citations 125

Authors

L Lakshmi Narayanan

C Vaishnavi

Affiliations

Soon will be listed here.

Abstract

Root canal therapy has been practiced ever since 1928 and the success rate has tremendously increased over the years owing to various advancements in the field. One main reason is the complete understanding of the microbiology involved in the endodontic pathology. This has helped us to modify the conventional treatment plans and effectively combat the microorganisms. Now, studies are aiming to explore the characteristics of the "most" resistant organism and the methods to eliminate them. This article gives an insight of the microbiology involved in endodontic pathology and discusses its role in our treatment procedure. Information from original reviews listed in PubMed, published from 1995 to 2010, has been mainly included in this review.

Citing Articles

Microbial Dynamics in Endodontic Pathology-From Bacterial Infection to Therapeutic Interventions-A Narrative Review.

Wieczorkiewicz K, Jarzabek A, Bakinowska E, Kielbowski K, Pawlik A Pathogens. 2025; 14(1).

PMID: 39860973 PMC: 11768076. DOI: 10.3390/pathogens14010012.

Immediate Patient Satisfaction with Dental Esthetics After Endodontic and Prosthodontic Treatment of Dental Dyschromia.

Jantea A, Mihali S, Lolos D, Tudor A, Oancea R, Porojan L Dent J (Basel). 2025; 13(1.

PMID: 39851620 PMC: 11764403. DOI: 10.3390/dj13010044.

Effect of Herbal Extract of and Cinnamon Oil on Biofilm Eradication: An Study.

Bhamare S, Dahake P, Kale Y, Dadpe M, Kendre S Int J Clin Pediatr Dent. 2024; 17(9):1004-1013.

PMID: 39664834 PMC: 11628687. DOI: 10.5005/jp-journals-10005-2922.

Towards Wiser Prescribing of Antibiotics in Dental Practice: What Pharmacists Want Dentists to Know.

Thabit A, Aljereb N, Khojah O, Shanab H, Badahdah A Dent J (Basel). 2024; 12(11).

PMID: 39590395 PMC: 11593279. DOI: 10.3390/dj12110345.

Quantitative analysis of antibacterial efficacy of herbal irrigants against endodontic microflora - A clinical study.

Das L, Maity I, Desai P, Mazumdar P, Ghosh K J Conserv Dent Endod. 2024; 27(10):1048-1053.

PMID: 39583280 PMC: 11581363. DOI: 10.4103/JCDE.JCDE_385_24.

References

Torabinejad M, Ung B, Kettering J . In vitro bacterial penetration of coronally unsealed endodontically treated teeth. J Endod. 1990; 16(12):566-9. DOI: 10.1016/S0099-2399(07)80198-1. View

Niederman R, Zhang J, KASHKET S . Short-chain carboxylic-acid-stimulated, PMN-mediated gingival inflammation. Crit Rev Oral Biol Med. 1997; 8(3):269-90. DOI: 10.1177/10454411970080030301. View

Wilson M . Susceptibility of oral bacterial biofilms to antimicrobial agents. J Med Microbiol. 1996; 44(2):79-87. DOI: 10.1099/00222615-44-2-79. View

Tomita H, Fujimoto S, Tanimoto K, Ike Y . Cloning and genetic and sequence analyses of the bacteriocin 21 determinant encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pPD1. J Bacteriol. 1997; 179(24):7843-55. PMC: 179750. DOI: 10.1128/jb.179.24.7843-7855.1997. View

Henderson B, Wilson M . Commensal communism and the oral cavity. J Dent Res. 1998; 77(9):1674-83. DOI: 10.1177/00220345980770090301. View

Tang G, Yip H, Samaranayake L, Chan K, Luo G, Fang H . Direct detection of cell surface interactive forces of sessile, fimbriated and non-fimbriated Actinomyces spp. using atomic force microscopy. Arch Oral Biol. 2004; 49(9):727-38. DOI: 10.1016/j.archoralbio.2004.04.003. View

Sakamoto M, Rocas I, Siqueira Jr J, Benno Y . Molecular analysis of bacteria in asymptomatic and symptomatic endodontic infections. Oral Microbiol Immunol. 2006; 21(2):112-22. DOI: 10.1111/j.1399-302X.2006.00270.x. View

Nair P . Apical periodontitis: a dynamic encounter between root canal infection and host response. Periodontol 2000. 1997; 13:121-48. DOI: 10.1111/j.1600-0757.1997.tb00098.x. View

Shah H, Collins D . Prevotella, a new genus to include Bacteroides melaninogenicus and related species formerly classified in the genus Bacteroides. Int J Syst Bacteriol. 1990; 40(2):205-8. DOI: 10.1099/00207713-40-2-205. View

10.

Costerton J, Stewart P, Greenberg E . Bacterial biofilms: a common cause of persistent infections. Science. 1999; 284(5418):1318-22. DOI: 10.1126/science.284.5418.1318. View

11.

Sundqvist G, Carlsson J, Herrmann B, Tarnvik A . Degradation of human immunoglobulins G and M and complement factors C3 and C5 by black-pigmented Bacteroides. J Med Microbiol. 1985; 19(1):85-94. DOI: 10.1099/00222615-19-1-85. View

12.

Love R . Enterococcus faecalis--a mechanism for its role in endodontic failure. Int Endod J. 2001; 34(5):399-405. DOI: 10.1046/j.1365-2591.2001.00437.x. View

13.

Schein B, Schilder H . Endotoxin content in endodontically involved teeth. J Endod. 1975; 1(1):19-21. DOI: 10.1016/S0099-2399(75)80244-5. View

14.

Tronstad L, Barnett F, Riso K, Slots J . Extraradicular endodontic infections. Endod Dent Traumatol. 1987; 3(2):86-90. DOI: 10.1111/j.1600-9657.1987.tb00549.x. View

15.

Caldwell D, Atuku E, Wilkie D, Wivcharuk K, Karthikeyan S, Korber D . Germ theory vs. community theory in understanding and controlling the proliferation of biofilms. Adv Dent Res. 1997; 11(1):4-13. DOI: 10.1177/08959374970110011501. View

16.

Nair P . On the causes of persistent apical periodontitis: a review. Int Endod J. 2006; 39(4):249-81. DOI: 10.1111/j.1365-2591.2006.01099.x. View

17.

Hogg S, Whiley R, de Soet J . Occurrence of lipoteichoic acid in oral streptococci. Int J Syst Bacteriol. 1997; 47(1):62-6. DOI: 10.1099/00207713-47-1-62. View

18.

Moine P, Abraham E . Immunomodulation and sepsis: impact of the pathogen. Shock. 2004; 22(4):297-308. DOI: 10.1097/01.shk.0000140663.80530.73. View

19.

Slots J . Herpesviruses in periodontal diseases. Periodontol 2000. 2005; 38:33-62. DOI: 10.1111/j.1600-0757.2005.00109.x. View

20.

Sunde P, Tronstad L, Eribe E, LIND P, Olsen I . Assessment of periradicular microbiota by DNA-DNA hybridization. Endod Dent Traumatol. 2001; 16(5):191-6. PMC: 7194203. DOI: 10.1034/j.1600-9657.2000.016005191.x. View