Can 'high-risk' Human Papillomaviruses (HPVs) Be Detected in Human Breast Milk?

Overview

Journal Acta Paediatr

Specialty Pediatrics

Date 2011 Jan 11

PMID 21214884

Citations 6

Authors

Ioannis N Mammas

Apostolos Zaravinos

George Sourvinos

Nikolaos Myriokefalitakis

Maria Theodoridou

Demetrios A Spandidos

Affiliations

Soon will be listed here.

Abstract

Aim: Human papillomavirus (HPV) transmission via nonsexual modes in childhood has been proposed by several researchers. The aim of our study was to determine the presence of 'high-risk' HPV DNA in human breast milk.

Methods: Using polymerase chain reaction techniques, we evaluated the presence of HPV infection in human breast milk collected from 21 HPV-positive and 11 HPV-negative mothers.

Results: Of the 32 studied human milk specimens, no 'high-risk' HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 or 58 DNA was detected.

Conclusion: This preliminary case-control study indicates the absence of mucosal 'high-risk' HPV types in human breast milk.

Citing Articles

Detection of Human Papillomaviruses in the Nasopharynx of Breastfed Infants: New Findings and Meta-Analysis.

Dassi L, Annunziata C, Botti C, Micillo A, Cerasuolo A, Starita N Viruses. 2020; 12(10).

PMID: 33019742 PMC: 7650825. DOI: 10.3390/v12101119.

HPV infection and bacterial microbiota in breast milk and infant oral mucosa.

Tuominen H, Rautava S, Collado M, Syrjanen S, Rautava J PLoS One. 2018; 13(11):e0207016.

PMID: 30395655 PMC: 6218085. DOI: 10.1371/journal.pone.0207016.

The philosophy of paediatric teaching: An interview with Dr Nikolaos Myriokefalitakis, former Clinical Director of the 'Penteli' Children's Hospital in Athens (Greece).

Mammas I, Spandidos D Exp Ther Med. 2018; 16(3):2799-2802.

PMID: 30186508 PMC: 6122465. DOI: 10.3892/etm.2018.6546.

The paediatric story of human papillomavirus (Review).

Mammas I, Sourvinos G, Spandidos D Oncol Lett. 2014; 8(2):502-506.

PMID: 25013461 PMC: 4081157. DOI: 10.3892/ol.2014.2226.

High-risk human papillomavirus (HPV) DNA sequences in metaplastic breast carcinomas of Mexican women.

Herrera-Goepfert R, Vela-Chavez T, Carrillo-Garcia A, Lizano-Soberon M, Amador-Molina A, Onate-Ocana L BMC Cancer. 2013; 13:445.

PMID: 24083491 PMC: 3852771. DOI: 10.1186/1471-2407-13-445.