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Livedoid Thrombotic Vasculopathy Responding to Doxycycline Therapy

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Date 2011 Jan 8
PMID 21212844
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Abstract

Livedoid vasculopathy is a disease of the lower extremities that occurs predominantly in women. It begins as purpura and eventually ulcerates. Multiple causes have been posited, but many cases are found to be idiopathic. Many treatment modalities have been attempted to control the disease process, but many cases remain difficult to treat, and, at times, the treatments have side effects that limit treatment. This is a case report in a small number of patients tested in unblinded fashion. We report the effective use of doxycycline in the treatment of long-standing livedoid vasculopathy in two patients.

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Bilgic A, Ozcobanoglu S, Bozca B, Alpsoy E Int J Womens Dermatol. 2022; 7(5Part A):588-599.

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References
1.
SAUER G . Pentoxifylline (Trental) therapy for the vasculitis of atrophie blanche. Arch Dermatol. 1986; 122(4):380-1. View

2.
Webster G, Del Rosso J . Anti-inflammatory activity of tetracyclines. Dermatol Clin. 2007; 25(2):133-5, v. DOI: 10.1016/j.det.2007.01.012. View

3.
Juan W, Chan Y, Lee J, Yang L, Hong H, Yang C . Livedoid vasculopathy: long-term follow-up results following hyperbaric oxygen therapy. Br J Dermatol. 2006; 154(2):251-5. DOI: 10.1111/j.1365-2133.2005.06843.x. View

4.
BARD J, Winkelmann R . Livedo vasculitis. Segmental hyalinizing vasculitis of the dermis. Arch Dermatol. 1967; 96(5):489-99. DOI: 10.1001/archderm.96.5.489. View

5.
Shornick J, Nicholes B, Bergstresser P, Gilliam J . Idiopathic atrophie blanche. J Am Acad Dermatol. 1983; 8(6):792-8. DOI: 10.1016/s0190-9622(83)80008-5. View