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[Children with Cancer and Respiratory Viral Infection: Epidemiology, Diagnosis and Treatment Options]

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Date 2010 Dec 25
PMID 21183254
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Abstract

Community-adquired respiratory viral infection is the most common cause of febrile infection in children, and an important cause of infection to consider in children with cancer. Nevertheless, there are few well-designed, controlled studies in this population, which makes it difficult to understand the importance, behaviour and management of these viruses in immunocompromised children. New diagnostic techniques in PCR-based microbiology, could provide many opportunities for early diagnosis, preventing the spread of the virus and to implement the correct therapy. It is important to design appropriate prospective studies to assess these types of infections in children with cancer. In this review we analyse the main studies published in the literature, evaluating the epidemiology, diagnosis and management of children with cancer and respiratory viral infection.

References
1.
Schenk T, Strahm B, Kontny U, Hufnagel M, Neumann-Haefelin D, Falcone V . Disseminated bocavirus infection after stem cell transplant. Emerg Infect Dis. 2008; 13(9):1425-7. PMC: 2857292. DOI: 10.3201/eid1309.070318. View

2.
Boeckh M, Englund J, Li Y, Miller C, Cross A, Fernandez H . Randomized controlled multicenter trial of aerosolized ribavirin for respiratory syncytial virus upper respiratory tract infection in hematopoietic cell transplant recipients. Clin Infect Dis. 2006; 44(2):245-9. DOI: 10.1086/509930. View

3.
Kampmann B, Cubitt D, Walls T, Naik P, Depala M, Samarasinghe S . Improved outcome for children with disseminated adenoviral infection following allogeneic stem cell transplantation. Br J Haematol. 2005; 130(4):595-603. DOI: 10.1111/j.1365-2141.2005.05649.x. View

4.
Kaiser L, Aubert J, Pache J, Deffernez C, Rochat T, Garbino J . Chronic rhinoviral infection in lung transplant recipients. Am J Respir Crit Care Med. 2006; 174(12):1392-9. DOI: 10.1164/rccm.200604-489OC. View

5.
Englund J, Piedra P, Jewell A, Patel K, Baxter B, Whimbey E . Rapid diagnosis of respiratory syncytial virus infections in immunocompromised adults. J Clin Microbiol. 1996; 34(7):1649-53. PMC: 229088. DOI: 10.1128/JCM.34.7.1649-1653.1996. View