Effect of Selected Accelerants on Setting Time and Biocompatibility of Mineral Trioxide Aggregate (MTA)

Overview

Journal Oral Surg Oral Med Oral Pathol Oral Radiol Endod

Publisher Elsevier

Specialties Dentistry
General Surgery

Date 2010 Dec 24

PMID 21176827

Citations 18

Authors

Amer Z AlAnezi

Qiang Zhu

Yu-Hsiung Wang

Kamran E Safavi

Jin Jiang

Affiliations

Soon will be listed here.

Abstract

Objective: Various additives have been suggested to be used with mineral trioxide aggregate (MTA) to improve its handling characteristics. The purpose of this study was to evaluate the effects of various additives on setting time and cell attachment on gray MTA (GMTA).

Study Design: Single-rooted caries-free teeth were split, and dentin disks with class I cavity were made and filled with test and control materials. Setting time was measured using Gilmore apparatus. Mouse MC3T3-E1 osteoblasts and L929 mouse fibroblasts were grown on dentin and GMTA disks. Cell attachment was examined under fluorescent microscope.

Results: Adding KY liquid, CaCl(2), and NaOCl to GMTA improved the handling properties and decreased setting time. Osteoblasts and fibroblasts attached and spread on GMTA mixed with additives in a manner similar to GMTA mixed with water.

Conclusions: The various additives could be possible substitutes to water to decrease MTA setting time. MTA is biocompatible when mixed with the various additives.

Citing Articles

Analysis of pulp histological response to pulpotomy performed with white mineral trioxide aggregate mixed with 2.25% sodium hypochlorite gel in humans: a randomized controlled clinical trial.

Karkoutly M, Alnour A, Alabdullah J, Abu Hasna A, Nam O, Jalloul D Sci Rep. 2024; 14(1):31471.

PMID: 39733128 PMC: 11682085. DOI: 10.1038/s41598-024-83158-0.

The effect of three additives on properties of mineral trioxide aggregate cements: a systematic review and meta-analysis of in vitro studies.

Bolhari B, Noori F, Assadian H, Raee A, Ghabraei S, Shamshiri A BMC Oral Health. 2024; 24(1):335.

PMID: 38486235 PMC: 10941624. DOI: 10.1186/s12903-024-04103-1.

Effects of Fucoidan Powder Combined with Mineral Trioxide Aggregate as a Direct Pulp-Capping Material.

Kim M, Hayashi M, Yu B, Lee T, Kim R, Jo D Polymers (Basel). 2022; 14(12).

PMID: 35745892 PMC: 9228542. DOI: 10.3390/polym14122315.

Biological and antimicrobial properties of the association Ambroxol and a water-soluble viscous liquid as a vehicle for a tricalcium silicate-based sealer.

De Azevedo Queiroz I, Machado T, Alves C, Brito V, Vasconcelos B, Gomes-Filho J J Mater Sci Mater Med. 2021; 32(12):140.

PMID: 34817700 PMC: 8613135. DOI: 10.1007/s10856-021-06604-9.

Fabrication and Characterization of a Nanofast Cement for Dental Restorations.

Yousefi K, Manesh H, Khalifeh A, Gholami A Biomed Res Int. 2021; 2021:7343147.

PMID: 34540997 PMC: 8448608. DOI: 10.1155/2021/7343147.