Epithelial-mesenchymal Transition in the Skin

Overview

Journal J Dermatol Sci

Publisher Elsevier

Specialty Dermatology

Date 2010 Dec 21

PMID 21167690

Citations 63

Authors

Motonobu Nakamura

Yoshiki Tokura

Affiliations

Soon will be listed here.

Abstract

Epithelial-mesenchymal transition (EMT) plays important roles not only in the morphogenesis but also in wound repair, tissue fibrosis and cancer progression. Recently, regulatory mechanism of this process has been elaborately elucidated. EMT can be a new therapeutic target for treating skin ulcer, fibrosing alopecia, and malignant cutaneous cancers, including squamous cell carcinoma and melanoma.

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