A Pharmacological Review on Intraperitoneal Chemotherapy for Peritoneal Malignancy

Overview

Journal World J Gastrointest Oncol

Publisher Baishideng Publishing Group

Date 2010 Dec 17

PMID 21160929

Citations 46

Authors

Tristan D Yan

Christopher Qian Cao

Stine Munkholm-Larsen

Affiliations

Soon will be listed here.

Abstract

Perioperative intraperitoneal chemotherapy in combination with cytoreductive surgery has been shown to be of benefit for treating selected patients with peritoneal surface malignancy. It has become a new standard of care in the management of diffuse malignant peritoneal mesothelioma and peritoneal dissemination of appendiceal malignancy. Numerous recent publications on carcinomatosis from colorectal cancer and gastric cancer identify groups of patients that would benefit from this local-regional approach for prevention and treatment of carcinomatosis. This review focuses on pharmacological information regarding intraperitoneal chemotherapeutic agents commonly used in gastrointestinal oncology.

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