Current Debate on the Use of Antibiotic Prophylaxis for Caesarean Section

Overview

Journal BJOG

Specialty Gynecology & Obstetrics

Date 2010 Dec 17

PMID 21159119

Citations 27

Authors

R F Lamont

J D Sobel

J P Kusanovic

E Vaisbuch

S Mazaki-Tovi

S K Kim

N Uldbjerg

R Romero

Affiliations

Soon will be listed here.

Abstract

Caesarean delivery is frequently complicated by surgical site infections, endometritis and urinary tract infection. Most surgical site infections occur after discharge from the hospital, and are increasingly being used as performance indicators. Worldwide, the rate of caesarean delivery is increasing. Evidence-based guidelines recommended the use of prophylactic antibiotics before surgical incision. An exception is made for caesarean delivery, where narrow-range antibiotics are administered after umbilical cord clamping because of putative neonatal benefit. However, recent evidence supports the use of pre-incision, broad-spectrum antibiotics, which result in a lower rate of maternal morbidity with no disadvantage to the neonate.

Citing Articles

Surgical site infection and antimicrobial use following caesarean section at QECH in Blantyre, Malawi: a prospective cohort study.

Kachipedzu A, Kulapani D, Meja S, Musaya J Antimicrob Resist Infect Control. 2024; 13(1):131.

PMID: 39473007 PMC: 11520451. DOI: 10.1186/s13756-024-01483-5.

A Comprehensive Case Report Emphasizing the Role of Caesarean Section, Antibiotic Prophylaxis, and Post-operative Care in Meconium-Stained Fetal Distress Syndrome.

E A, S N, Subramanian A, T T, Vellapandian C, J N Cureus. 2024; 16(8):e66123.

PMID: 39229399 PMC: 11370710. DOI: 10.7759/cureus.66123.

State of the art: Intrapartum antibiotics in cesarean section, the infant microbiota and allergic diseases.

Moore J, Navarro S, McCarthy K, Rashid R, Phipps S, Amoako A Acta Obstet Gynecol Scand. 2023; 102(7):811-820.

PMID: 37067195 PMC: 10333666. DOI: 10.1111/aogs.14577.

Evaluation of the practice of surgical antibiotic prophylaxis in a Zonal Referral Hospital in Mbujimayi, Democratic Republic of the Congo (DRC).

Mbuyamba H, Muamba C, Binene S, Uwonda S BMC Surg. 2023; 23(1):28.

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Role of short interpregnancy interval, birth mode, birth practices, and the postpartum vaginal microbiome in preterm birth.

Odogwu N Front Reprod Health. 2023; 4:1082199.

PMID: 36685092 PMC: 9845938. DOI: 10.3389/frph.2022.1082199.

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