Distinction of Phyllodes Tumor from Fibroadenoma: Cytologists' Perspective

Overview

Journal J Cytol

Specialty Cell Biology

Date 2010 Dec 16

PMID 21157551

Citations 3

Authors

Ranjana Bandyopadhyay

Dipanwita Nag

Santosh Kumar Mondal

Subhalakshmi Mukhopadhyay

Sumit Roy

Swapan Kumar Sinha

Affiliations

Soon will be listed here.

Abstract

Background: Fibroadenomas and phyllodes tumors may have similar cytological appearances. However, a detailed study of cytomorphology of stromal elements may be helpful in differentiation.

Aim: To evaluate the cytological features of phyllodes tumor in our study with special reference to features that can help distinguishing it from fibroadenoma.

Materials And Methods: The archival materials of our hospital were searched from January 2006 to January 2009 for histopathologically-diagnosed cases of phyllodes tumor. The cases in which previous cytopathology smears were available were included in the study. The cytomorphology of 10 such cases were compared with 25 cytologically-diagnosed and histopathologically-confirmed cases of fibroadenoma.

Results: The size, cellularity of stromal fragments, and the proportion of spindle cells in the background are important features in such differentiation.

Citing Articles

Phyllodes Tumor, A Cytomorphologic Study of 17 Cases with Histologic Correlation.

Agarwal S, Pandey P, Sawhney M, Yadav A, Meena S Iran J Pathol. 2025; 20(1):90-97.

PMID: 40060234 PMC: 11887631. DOI: 10.30699/ijp.2024.2033852.3322.

Fibroadenoma versus phyllodes tumor: a vexing problem revisited!.

Tummidi S, Kothari K, Agnihotri M, Naik L, Sood P BMC Cancer. 2020; 20(1):648.

PMID: 32660435 PMC: 7359567. DOI: 10.1186/s12885-020-07129-0.

An 11 kg Phyllodes tumor of the breast in combination with other multiple chronic diseases: Case report and review of the literature.

Zhao Z, Zhang J, Chen Y, Shen L, Wang J Oncol Lett. 2013; 6(1):150-152.

PMID: 23946794 PMC: 3742775. DOI: 10.3892/ol.2013.1361.

The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation.

Muddegowda P, Lingegowda J, Kurpad R, Konapur P, Shivarudrappa A, Subramaniam P J Cytol. 2011; 28(1):13-9.

PMID: 21552401 PMC: 3083528. DOI: 10.4103/0970-9371.76942.

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