Taxane Pathway

Overview

Journal Pharmacogenet Genomics

Specialties Genetics
Pharmacology

Date 2010 Dec 15

PMID 21151855

Citations 23

Authors

Connie Oshiro

Sharon Marsh

Howard Mcleod

Michelle Whirl Carrillo

Teri Klein

Russ Altman

Affiliations

Soon will be listed here.

Citing Articles

Inducing breast cancer cell death: The impact of taxodone on proliferation through apoptosis.

Bakhsh T, Alyami N Heliyon. 2024; 10(13):e34044.

PMID: 39055854 PMC: 11269907. DOI: 10.1016/j.heliyon.2024.e34044.

Prediction models of persistent taxane-induced peripheral neuropathy among breast cancer survivors using whole-exome sequencing.

Engvall K, Uvdal H, Bjorn N, Avall-Lundqvist E, Green H NPJ Precis Oncol. 2024; 8(1):102.

PMID: 38755266 PMC: 11099113. DOI: 10.1038/s41698-024-00594-x.

circRNAs in drug resistance of breast cancer.

Misir S, Yaman S, Petrovic N, Sumer C, Hepokur C, Aliyazicioglu Y Oncol Res. 2023; 30(4):157-172.

PMID: 37304411 PMC: 10208077. DOI: 10.32604/or.2022.027547.

Leveraging GWAS data derived from a large cooperative group trial to assess the risk of taxane-induced peripheral neuropathy (TIPN) in patients being treated for breast cancer: Part 2-functional implications of a SNP cluster associated with TIPN....

Lustberg M, Wu X, Fernandez-Martinez J, de Andres-Galiana E, Philips S, Leibowitz J Support Care Cancer. 2023; 31(3):178.

PMID: 36809570 PMC: 11344472. DOI: 10.1007/s00520-023-07617-6.

Targeting Mitochondria and Oxidative Stress in Cancer- and Chemotherapy-Induced Muscle Wasting.

Huot J, Baumfalk D, Resendiz A, Bonetto A, Smuder A, Penna F Antioxid Redox Signal. 2022; 38(4-6):352-370.

PMID: 36310444 PMC: 10081727. DOI: 10.1089/ars.2022.0149.

References

Berman H, Westbrook J, Feng Z, Gilliland G, Bhat T, Weissig H . The Protein Data Bank. Nucleic Acids Res. 1999; 28(1):235-42. PMC: 102472. DOI: 10.1093/nar/28.1.235. View

Cresteil T, Monsarrat B, Dubois J, Sonnier M, Alvinerie P, Gueritte F . Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship. Drug Metab Dispos. 2002; 30(4):438-45. DOI: 10.1124/dmd.30.4.438. View

Harmsen S, Meijerman I, Beijnen J, Schellens J . Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor. Cancer Chemother Pharmacol. 2008; 64(1):35-43. DOI: 10.1007/s00280-008-0842-3. View

Haldar S, Basu A, Croce C . Bcl2 is the guardian of microtubule integrity. Cancer Res. 1997; 57(2):229-33. View

Gelderblom H, Verweij J, Nooter K, Sparreboom A . Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur J Cancer. 2001; 37(13):1590-8. DOI: 10.1016/s0959-8049(01)00171-x. View

Brooks T, Minderman H, OLoughlin K, Pera P, Ojima I, Baer M . Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein. Mol Cancer Ther. 2003; 2(11):1195-205. View

Chang H, Rha S, Jeung H, Im C, Ahn J, Kwon W . Association of the ABCB1 gene polymorphisms 2677G>T/A and 3435C>T with clinical outcomes of paclitaxel monotherapy in metastatic breast cancer patients. Ann Oncol. 2008; 20(2):272-7. DOI: 10.1093/annonc/mdn624. View

Monzo M, Rosell R, Sanchez J, Lee J, OBrate A, Gonzalez-Larriba J . Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations. J Clin Oncol. 1999; 17(6):1786-93. DOI: 10.1200/JCO.1999.17.6.1786. View

Green H, Soderkvist P, Rosenberg P, Horvath G, Peterson C . mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy. Clin Cancer Res. 2006; 12(3 Pt 1):854-9. DOI: 10.1158/1078-0432.CCR-05-0950. View

10.

Synold T, Dussault I, Forman B . The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat Med. 2001; 7(5):584-90. DOI: 10.1038/87912. View

11.

Allen J, Brinkhuis R, van Deemter L, Wijnholds J, Schinkel A . Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance. Cancer Res. 2000; 60(20):5761-6. View

12.

Tsurutani J, Komiya T, Uejima H, Tada H, Syunichi N, Oka M . Mutational analysis of the beta-tubulin gene in lung cancer. Lung Cancer. 2001; 35(1):11-6. DOI: 10.1016/s0169-5002(01)00291-4. View

13.

Maeno K, Ito K, Hama Y, Shingu K, Kimura M, Sano M . Mutation of the class I beta-tubulin gene does not predict response to paclitaxel for breast cancer. Cancer Lett. 2003; 198(1):89-97. DOI: 10.1016/s0304-3835(03)00279-9. View

14.

Gardner E, Dahut W, Scripture C, Jones J, Aragon-Ching J, Desai N . Randomized crossover pharmacokinetic study of solvent-based paclitaxel and nab-paclitaxel. Clin Cancer Res. 2008; 14(13):4200-5. PMC: 2661025. DOI: 10.1158/1078-0432.CCR-07-4592. View

15.

Marsh S, Paul J, King C, Gifford G, McLeod H, Brown R . Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: the Scottish Randomised Trial in Ovarian Cancer. J Clin Oncol. 2007; 25(29):4528-35. DOI: 10.1200/JCO.2006.10.4752. View

16.

Smith N, Marsh S, Scott-Horton T, Hamada A, Mielke S, Mross K . Variants in the SLCO1B3 gene: interethnic distribution and association with paclitaxel pharmacokinetics. Clin Pharmacol Ther. 2006; 81(1):76-82. DOI: 10.1038/sj.clpt.6100011. View

17.

Nakajima M, Fujiki Y, Kyo S, Kanaya T, Nakamura M, Maida Y . Pharmacokinetics of paclitaxel in ovarian cancer patients and genetic polymorphisms of CYP2C8, CYP3A4, and MDR1. J Clin Pharmacol. 2005; 45(6):674-82. DOI: 10.1177/0091270005276204. View

18.

Gianni L, Kearns C, Giani A, Capri G, Vigano L, Lacatelli A . Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans. J Clin Oncol. 1995; 13(1):180-90. DOI: 10.1200/JCO.1995.13.1.180. View

19.

Zhou J, Giannakakou P . Targeting microtubules for cancer chemotherapy. Curr Med Chem Anticancer Agents. 2005; 5(1):65-71. DOI: 10.2174/1568011053352569. View

20.

Lowe J, Li H, Downing K, Nogales E . Refined structure of alpha beta-tubulin at 3.5 A resolution. J Mol Biol. 2001; 313(5):1045-57. DOI: 10.1006/jmbi.2001.5077. View