Editors' Pick 2010

Overview

Journal Br J Clin Pharmacol

Specialty Pharmacology

Date 2010 Dec 15

PMID 21143495

Authors

Yoon K Loke

Albert Ferro

Lionel D Lewis

Adam F Cohen

Andrew Somogyi

James M Ritter

Affiliations

Soon will be listed here.

References

Chen C, Willis B, Mooney L, Ong G, Lim C, Lowe S . Cortisol response to individualised graded insulin infusions: a reproducible biomarker for CNS compounds inhibiting HPA activation. Br J Clin Pharmacol. 2010; 70(6):886-94. PMC: 3014072. DOI: 10.1111/j.1365-2125.2010.03781.x. View

Donado E, Izquierdo I, Perez I, Garcia O, Antonijoan R, Gich I . No cardiac effects of therapeutic and supratherapeutic doses of rupatadine: results from a 'thorough QT/QTc study' performed according to ICH guidelines. Br J Clin Pharmacol. 2010; 69(4):401-10. PMC: 2848413. DOI: 10.1111/j.1365-2125.2009.03599.x. View

Hoffman R . Treatment of patients with cocaine-induced arrhythmias: bringing the bench to the bedside. Br J Clin Pharmacol. 2010; 69(5):448-57. PMC: 2856045. DOI: 10.1111/j.1365-2125.2010.03632.x. View

Newsome B, Ernstoff M . The clinical pharmacology of therapeutic monoclonal antibodies in the treatment of malignancy; have the magic bullets arrived?. Br J Clin Pharmacol. 2008; 66(1):6-19. PMC: 2485255. DOI: 10.1111/j.1365-2125.2008.03187.x. View

Fang Z, Zhang Y, Ge G, Huo H, Liang S, Yang L . Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction. Br J Clin Pharmacol. 2010; 69(2):193-9. PMC: 2824481. DOI: 10.1111/j.1365-2125.2009.03572.x. View

Waring W, Graham A, Gray J, Wilson A, Howell C, Bateman D . Evaluation of a QT nomogram for risk assessment after antidepressant overdose. Br J Clin Pharmacol. 2010; 70(6):881-5. PMC: 3014071. DOI: 10.1111/j.1365-2125.2010.03728.x. View

Berendt L, Hakansson C, Bach K, Andreasen P, Petersen L, Andersen E . Methodological characteristics of academic clinical drug trials--a retrospective cohort study of applications to the Danish Medicines Agency 1993-2005. Br J Clin Pharmacol. 2010; 70(5):729-35. PMC: 2997313. DOI: 10.1111/j.1365-2125.2010.03755.x. View

Lee S, Jang Y, Cha E, Kim H, Lee S, Shin J . A haplotype of CYP2C9 associated with warfarin sensitivity in mechanical heart valve replacement patients. Br J Clin Pharmacol. 2010; 70(2):213-21. PMC: 2911551. DOI: 10.1111/j.1365-2125.2010.03688.x. View

Paris A, Brandt C, Cornu C, Maison P, Thalamas C, Cracowski J . Informed consent document improvement does not increase patients' comprehension in biomedical research. Br J Clin Pharmacol. 2010; 69(3):231-7. PMC: 2829692. DOI: 10.1111/j.1365-2125.2009.03565.x. View

10.

Sibille M, Patat A, Caplain H, Donazzolo Y . A safety grading scale to support dose escalation and define stopping rules for healthy subject first-entry-into-man studies: some points to consider from the French Club Phase I working group. Br J Clin Pharmacol. 2010; 70(5):736-48. PMC: 2997314. DOI: 10.1111/j.1365-2125.2010.03741.x. View

11.

Street J, Dear J . The application of mass-spectrometry-based protein biomarker discovery to theragnostics. Br J Clin Pharmacol. 2010; 69(4):367-78. PMC: 2848410. DOI: 10.1111/j.1365-2125.2009.03610.x. View

12.

Duerden M, Hughes D . Generic and therapeutic substitutions in the UK: are they a good thing?. Br J Clin Pharmacol. 2010; 70(3):335-41. PMC: 2949903. DOI: 10.1111/j.1365-2125.2010.03718.x. View

13.

Davies E, Green C, Mottram D, Pirmohamed M . Interpreting adverse drug reaction (ADR) reports as hospital patient safety incidents. Br J Clin Pharmacol. 2010; 70(1):102-8. PMC: 2909812. DOI: 10.1111/j.1365-2125.2010.03671.x. View

14.

Heiss M, Murawa P, Koralewski P, Kutarska E, Kolesnik O, Ivanchenko V . The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial. Int J Cancer. 2010; 127(9):2209-21. PMC: 2958458. DOI: 10.1002/ijc.25423. View

15.

Abdul M, Jiang X, Williams K, Day R, Roufogalis B, Liauw W . Pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects. Br J Clin Pharmacol. 2010; 69(5):508-15. PMC: 2856051. DOI: 10.1111/j.1365-2125.2010.03620.x. View

16.

Rasmussen M, Colding-Jorgensen M, Hansen L, Bro R . Multivariate evaluation of pharmacological responses in early clinical trials - a study of rIL-21 in the treatment of patients with metastatic melanoma. Br J Clin Pharmacol. 2010; 69(4):379-90. PMC: 2848411. DOI: 10.1111/j.1365-2125.2009.03600.x. View

17.

Wood D, Dargan P . Putting cocaine use and cocaine-associated cardiac arrhythmias into epidemiological and clinical perspective. Br J Clin Pharmacol. 2010; 69(5):443-7. PMC: 2856044. DOI: 10.1111/j.1365-2125.2010.03630.x. View

18.

Taubel J, Naseem A, Harada T, Wang D, Arezina R, Lorch U . Levofloxacin can be used effectively as a positive control in thorough QT/QTc studies in healthy volunteers. Br J Clin Pharmacol. 2010; 69(4):391-400. PMC: 2848412. DOI: 10.1111/j.1365-2125.2009.03595.x. View

19.

Cen H, Zeng W, Leng X, Huang M, Chen X, Li J . CYP4F2 rs2108622: a minor significant genetic factor of warfarin dose in Han Chinese patients with mechanical heart valve replacement. Br J Clin Pharmacol. 2010; 70(2):234-40. PMC: 2911553. DOI: 10.1111/j.1365-2125.2010.03698.x. View

20.

Ruf P, Kluge M, Jager M, Burges A, Volovat C, Heiss M . Pharmacokinetics, immunogenicity and bioactivity of the therapeutic antibody catumaxomab intraperitoneally administered to cancer patients. Br J Clin Pharmacol. 2010; 69(6):617-25. PMC: 2878603. DOI: 10.1111/j.1365-2125.2010.03635.x. View