Cutaneous Leishmaniasis (Leishmania Major Infection) in Dutch Troops Deployed in Northern Afghanistan: Epidemiology, Clinical Aspects, and Treatment

Overview

Journal Am J Trop Med Hyg

Specialty Tropical Medicine

Date 2010 Dec 2

PMID 21118937

Citations 26

Authors

Pieter-Paul van Thiel

Tjalling Leenstra

Henry J de Vries

Allard van der Sluis

Tom van Gool

Alex C Krull

Michele van Vugt

Peter J de Vries

Jimmy E Zeegelaar

Aldert Bart

Wendy F van der Meide

Henk D F H Schallig

William R Faber

Piet A Kager

Affiliations

Soon will be listed here.

Abstract

Cutaneous leishmaniasis caused by Leishmania major infection affected 172 (18.3%) of 938 Dutch military troops deployed in northern Afghanistan in 2005. The high attack rate was a result of initial insufficient availability of means of prevention and insufficient adherence to preventive measures. At presentation, the lymphatic system was involved in 24.8%. Treatment with intralesional injections of antimony with or without cryotherapy was satisfactory, but 19.5% of patients received secondary treatment with miltefosine. Six months after treatment, 128 (77.1%) of 166 treated patients were cured, 16 (9.6%) were lost to follow-up, and 22 (13.3%) already experienced cure at six weeks but were not seen at six months. Natural evolution played a role in this observational study, which showed cure of all patients seen at six months. In general, management of cutaneous leishmaniasis was feasible under field conditions.

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