Dermatofibrosarcoma Protuberans: a Case Report and Review of the Literature

Overview

Journal J Clin Aesthet Dermatol

Date 2010 Nov 25

PMID 21103308

Citations 19

Authors

Sanjay Bhambri

Avani Desai

James Q Del Rosso

Narciss Mobini

Affiliations

Soon will be listed here.

Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing fibrohistiocytic neoplasm that commonly favors young to middle-aged adults. It is most commonly seen on the trunk and frequently recurs locally after an incomplete excision, but distant metastasis is rare. Mohs micrographic surgery (MMS) is the treatment of choice for DFSP.

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References

Mendenhall W, Zlotecki R, Scarborough M . Dermatofibrosarcoma protuberans. Cancer. 2004; 101(11):2503-8. DOI: 10.1002/cncr.20678. View

Abrams T, Schuetze S . Targeted therapy for dermatofibrosarcoma protuberans. Curr Oncol Rep. 2007; 8(4):291-6. DOI: 10.1007/s11912-006-0035-3. View

Snow S, Gordon E, Larson P, Bagheri M, Bentz M, Sable D . Dermatofibrosarcoma protuberans: a report on 29 patients treated by Mohs micrographic surgery with long-term follow-up and review of the literature. Cancer. 2004; 101(1):28-38. DOI: 10.1002/cncr.20316. View

Haycox C, Odland P, Olbricht S, Casey B . Dermatofibrosarcoma protuberans (DFSP): growth characteristics based on tumor modeling and a review of cases treated with Mohs micrographic surgery. Ann Plast Surg. 1997; 38(3):246-51. View

Gloster Jr H . Dermatofibrosarcoma protuberans. J Am Acad Dermatol. 1996; 35(3 Pt 1):355-74; quiz 375-6. DOI: 10.1016/s0190-9622(96)90597-6. View

McArthur G . Dermatofibrosarcoma protuberans: recent clinical progress. Ann Surg Oncol. 2007; 14(10):2876-86. DOI: 10.1245/s10434-007-9480-y. View

Criscione V, Weinstock M . Descriptive epidemiology of dermatofibrosarcoma protuberans in the United States, 1973 to 2002. J Am Acad Dermatol. 2006; 56(6):968-73. DOI: 10.1016/j.jaad.2006.09.006. View

Beech D, Long A, Long W . Dermatofibrosarcoma protuberans and breast cancer: genetic link or coincidental association?. Am Surg. 2004; 70(6):543-5. View

Ballo M, Zagars G, Pisters P, Pollack A . The role of radiation therapy in the management of dermatofibrosarcoma protuberans. Int J Radiat Oncol Biol Phys. 1998; 40(4):823-7. DOI: 10.1016/s0360-3016(97)00895-x. View

10.

Zelger B, Ofner D, Zelger B . Atrophic variants of dermatofibroma and dermatofibrosarcoma protuberans. Histopathology. 1995; 26(6):519-27. DOI: 10.1111/j.1365-2559.1995.tb00270.x. View

11.

Stojadinovic A, Karpoff H, Antonescu C, Shah J, Singh B, SPIRO R . Dermatofibrosarcoma protuberans of the head and neck. Ann Surg Oncol. 2000; 7(9):696-704. DOI: 10.1007/s10434-000-0696-3. View

12.

Mentzel T, Scharer L, Kazakov D, Michal M . Myxoid dermatofibrosarcoma protuberans: clinicopathologic, immunohistochemical, and molecular analysis of eight cases. Am J Dermatopathol. 2007; 29(5):443-8. DOI: 10.1097/DAD.0b013e318145413c. View

13.

Reddy C, Hayward P, Thompson P, Kan A . Dermatofibrosarcoma protuberans in children. J Plast Reconstr Aesthet Surg. 2007; 62(6):819-23. DOI: 10.1016/j.bjps.2007.11.009. View

14.

Asuquo M, Umoh M, Ebughe G . Dermatofibrosarcoma protuberance: case reports. Ann Afr Med. 2008; 6(2):80-3. DOI: 10.4103/1596-3519.55710. View

15.

Nouri K, Lodha R, Jimenez G, Robins P . Mohs micrographic surgery for dermatofibrosarcoma protuberans: University of Miami and NYU experience. Dermatol Surg. 2002; 28(11):1060-4; discussion 1064. DOI: 10.1046/j.1524-4725.2002.02084.x. View

16.

Ruiz-Tovar J, Fernandez Guarino M, Reguero Callejas M, Aguilera Velardo A, Arano Bermejo J, Cabanas Navarro L . Dermatofibrosarcoma protuberans: review of 20-years experience. Clin Transl Oncol. 2006; 8(8):606-10. DOI: 10.1007/s12094-006-0067-z. View

17.

Behroozan D, Glaich A, Goldberg L . Dermatofibrosarcoma protuberans following tanning bed use. J Drugs Dermatol. 2005; 4(6):751-4. View

18.

Hanabusa M, Kamo R, Harada T, Ishii M . Dermatofibrosarcoma protuberans with atrophic appearance at early stage of the tumor. J Dermatol. 2007; 34(5):336-9. DOI: 10.1111/j.1346-8138.2007.00283.x. View

19.

Adler N, Tsabari C, Sulkes J, Ad-El D, Feinmesser M . Cyclooxygenase-2 expression in dermatofibroma and dermatofibrosarcoma protuberans. J Cutan Pathol. 2008; 35(6):532-5. DOI: 10.1111/j.1600-0560.2007.00855.x. View

20.

Abenoza P, Lillemoe T . CD34 and factor XIIIa in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans. Am J Dermatopathol. 1993; 15(5):429-34. DOI: 10.1097/00000372-199310000-00003. View