Stress and Allergic Diseases

Overview

Journal Immunol Allergy Clin North Am

Specialty Allergy & Immunology

Date 2010 Nov 25

PMID 21094923

Citations 36

Authors

Ninabahen D Dave

Lianbin Xiang

Kristina E Rehm

Gailen D Marshall Jr

Affiliations

Soon will be listed here.

Abstract

Allergy describes a constellation of clinical diseases that affect up to 30% of the world's population. It is characterized by production of allergen-specific IgE, which binds to mast cells and initiates a cascade of molecular and cellular events that affect the respiratory tract (rhinitis and asthma), skin (dermatitis, urticaria), and multiple systems (anaphylaxis) in response to a variety of allergens including pollens, mold spores, animal danders, insect stings, foods, and drugs. The underlying pathophysiology involves immunoregulatory dysfunctions similar to those noted in highly stressed populations. The relationships in terms of potential for intervention are discussed.

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