Cryptococcal Immune Reconstitution Syndrome During Steroid Withdrawal Treated with Hydroxychloroquine

Overview

Journal Int J Infect Dis

Publisher Elsevier

Specialty Infectious Diseases

Date 2010 Nov 25

PMID 21094071

Citations 10

Authors

Shivakumar Narayanan

Chandralekha Banerjee

Peter A Holt

Affiliations

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Abstract

We present a case report of cryptococcal immune reconstitution syndrome (IRS), in a non HIV infected patient, which we treated with hydroxychloroquine with successful results. We briefly review cryptococcal IRS, possible mechanisms of action of hydroxychloroquine as an immunomodulatory agent, and its potential role in management of IRS.

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