» Articles » PMID: 21085872

[Delayed Diagnosis of Malaria in a Dengue Endemic Area in the Brazilian Extra-Amazon: Recent Experience of a Malaria Surveillance Unit in State of Rio De Janeiro]

Abstract

Introduction: The mortality of malaria in the extra-Amazon region is about 80 times higher than in the Amazon region, where malaria is concentrated (99.8% of cases). In areas of dengue transmission, delay in the diagnosis and treatment of malaria in patients with fever who reside in areas of malaria transmission can be due to the confusion between the clinical diagnoses of both diseases by nonspecialist doctors, among other factors. This work presents some of the consequences of delayed diagnosis in three patients with malaria by Plasmodium falciparum, P. malariae and P. vivax, who, after following the usual route for Dengue treatment, sought our institution, where they were correctly diagnosed and adequately treated.

Methods: Description of three cases of malaria with delayed diagnosed malaria referred to the Outpatient Clinic for Acute Febrile Diseases, IPEC/FIOCRUZ-RJ, between 2007 and 2008.

Results: A Brazilian from Mozambique, primo-infected with P. falciparum was diagnosed with malaria six days after the onset of fever and died of cerebral malaria and shock. Another patient with P.malariae malaria presented a severe and prolonged course, but was cured after specific treatment. A third patient, with delayed diagnosis of P. vivax malaria, acquired it in the Atlantic Forest region in the State of Rio.

Conclusions: Health professionals from non-endemic areas for malaria should be trained to optimize the surveillance and early treatment of malaria and prevent morbid and fatal outcomes. An investigation of outbreaks of autochthonous malaria in the State of Rio de Janeiro is suggested.

Citing Articles

Malaria Mortality in Brazil: Age-Period-Cohort Effects, Sociodemographic Factors, and Sustainable Development Indicators.

Farias M, Figueiredo E, Silva R, Galhardo D, da Silva C, Moreira E Trop Med Infect Dis. 2025; 10(2).

PMID: 39998045 PMC: 11860777. DOI: 10.3390/tropicalmed10020041.


Autochthonous simian malaria in Brazil outside the Amazon: Emergence, zoonotic transmission and implications for disease control.

da Silva B, Lourenco-de-Oliveira R, de Aguiar Barros J, Brasil P, Daniel-Ribeiro C, de Fatima Ferreira da Cruz M One Health. 2024; 19:100928.

PMID: 39650148 PMC: 11621506. DOI: 10.1016/j.onehlt.2024.100928.


Sociodemographic aspects, time series and high-risk clusters of malaria in the extra-Amazon region of Brazil: a 22-year study.

Ramos R, Reis E, Bezerra L, Lima M, Feitosa A, Alves L Rev Soc Bras Med Trop. 2024; 57.

PMID: 39536215 PMC: 11656533. DOI: 10.1590/0037-8682-0564-2023.


A fatal respiratory complication of malaria caused by Plasmodium vivax.

Lopez A, Martins E, Pina-Costa A, Pacheco-Silva A, Ferreira M, Mamani R Malar J. 2023; 22(1):303.

PMID: 37814260 PMC: 10563287. DOI: 10.1186/s12936-023-04720-1.


Changes in malaria patterns in Brazil over 28 years (1990-2017): results from the Global Burden of Disease Study 2017.

Bezerra J, Barbosa D, Martins-Melo F, Werneck G, Braga E, Tauil P Popul Health Metr. 2020; 18(Suppl 1):5.

PMID: 32993671 PMC: 7526087. DOI: 10.1186/s12963-020-00211-6.