[Complications Due to Contrast Agent Administration: What Has Been Confirmed in Prevention?]

Overview

Journal Internist (Berl)

Specialty General Medicine

Date 2010 Nov 17

PMID 21079904

Citations 2

Authors

E Schonenberger

M Muhler

M Dewey

Affiliations

Soon will be listed here.

Abstract

Computed tomography (CT) and magnetic resonance imaging (MRI) have been evaluated by internists to be the most important medical innovations. Often, intravenous contrast agent administration is required for answering the clinical questions to CT and MRI. In this review we present an overview of the most common and most important aspects that need to be considered prior to intravenous contrast agent administration. We discuss aspects of renal impairment (contrast-induced nephropathy, nephrogenic systemic fibrosis), allergy-like reactions, hyperthyroidism, and pregnancy and breast-feeding.

Citing Articles

[Drug therapy in interventional radiology].

Sumkauskaite M, Bryant M, Kortes N, Stampfl U, Radeleff B Radiologe. 2015; 55(6):501-9.

PMID: 26063076 DOI: 10.1007/s00117-015-2808-x.

Delayed cardiac tamponade after open heart surgery - is supplemental CT imaging reasonable?.

Floerchinger B, Camboni D, Schopka S, Kolat P, Hilker M, Schmid C J Cardiothorac Surg. 2013; 8:158.

PMID: 23800191 PMC: 3698060. DOI: 10.1186/1749-8090-8-158.

References

Goergen S, Rumbold G, Compton G, Harris C . Systematic review of current guidelines, and their evidence base, on risk of lactic acidosis after administration of contrast medium for patients receiving metformin. Radiology. 2009; 254(1):261-9. DOI: 10.1148/radiol.09090690. View

Davidson C, Stacul F, McCullough P, Tumlin J, Adam A, Lameire N . Contrast medium use. Am J Cardiol. 2006; 98(6A):42K-58K. DOI: 10.1016/j.amjcard.2006.01.023. View

Thomsen H, Morcos S . Management of acute adverse reactions to contrast media. Eur Radiol. 2004; 14(3):476-81. DOI: 10.1007/s00330-003-2214-z. View

Cowper S, Robin H, Steinberg S, Su L, Gupta S, Leboit P . Scleromyxoedema-like cutaneous diseases in renal-dialysis patients. Lancet. 2000; 356(9234):1000-1. DOI: 10.1016/S0140-6736(00)02694-5. View

Hylton N . Suspension of breast-feeding following gadopentetate dimeglumine administration. Radiology. 2000; 216(2):325-6. DOI: 10.1148/radiology.216.2.r00au55325. View

Schreyer A, Debl K, Herfarth H . [Indications for magnetic resonance imaging in Internal Medicine. When do we really need this technology?]. Internist (Berl). 2010; 51(4):451-62. DOI: 10.1007/s00108-009-2452-5. View

Poletti P, Saudan P, Platon A, Mermillod B, Sautter A, Vermeulen B . I.v. N-acetylcysteine and emergency CT: use of serum creatinine and cystatin C as markers of radiocontrast nephrotoxicity. AJR Am J Roentgenol. 2007; 189(3):687-92. DOI: 10.2214/AJR.07.2356. View

Katayama H, Yamaguchi K, Kozuka T, Takashima T, Seez P, Matsuura K . Adverse reactions to ionic and nonionic contrast media. A report from the Japanese Committee on the Safety of Contrast Media. Radiology. 1990; 175(3):621-8. DOI: 10.1148/radiology.175.3.2343107. View

Davenport M, Cohan R, Caoili E, Ellis J . Repeat contrast medium reactions in premedicated patients: frequency and severity. Radiology. 2009; 253(2):372-9. DOI: 10.1148/radiol.2532090465. View

10.

Kielstein J, Schiffer M . [Nephrogenic systemic fibrosis: a rare disease with grave consequences]. Internist (Berl). 2009; 51(1):39-44. DOI: 10.1007/s00108-009-2408-9. View

11.

Fuchs V, Sox Jr H . Physicians' views of the relative importance of thirty medical innovations. Health Aff (Millwood). 2001; 20(5):30-42. DOI: 10.1377/hlthaff.20.5.30. View

12.

Reed M, Meier P, Tamhane U, Welch K, Moscucci M, Gurm H . The relative renal safety of iodixanol compared with low-osmolar contrast media: a meta-analysis of randomized controlled trials. JACC Cardiovasc Interv. 2009; 2(7):645-54. DOI: 10.1016/j.jcin.2009.05.002. View

13.

Bruce R, Djamali A, Shinki K, Michel S, Fine J, Pozniak M . Background fluctuation of kidney function versus contrast-induced nephrotoxicity. AJR Am J Roentgenol. 2009; 192(3):711-8. DOI: 10.2214/AJR.08.1413. View

14.

Hoste E, De Waele J, Gevaert S, Uchino S, Kellum J . Sodium bicarbonate for prevention of contrast-induced acute kidney injury: a systematic review and meta-analysis. Nephrol Dial Transplant. 2009; 25(3):747-58. DOI: 10.1093/ndt/gfp389. View

15.

Junkermann H . [Indications and contraindications for contrast-enhanced MRI and CT during pregnancy]. Radiologe. 2007; 47(9):774-7. DOI: 10.1007/s00117-007-1542-4. View

16.

Prince M, Zhang H, Morris M, MacGregor J, Grossman M, Silberzweig J . Incidence of nephrogenic systemic fibrosis at two large medical centers. Radiology. 2008; 248(3):807-16. DOI: 10.1148/radiol.2483071863. View

17.

Katzberg R, Newhouse J . Intravenous contrast medium-induced nephrotoxicity: is the medical risk really as great as we have come to believe?. Radiology. 2010; 256(1):21-8. DOI: 10.1148/radiol.10092000. View

18.

Nielsen S, MATHESON I, Rasmussen J, Skinnemoen K, Andrew E, Hafsahl G . Excretion of iohexol and metrizoate in human breast milk. Acta Radiol. 1987; 28(5):523-6. View

19.

Kanny G, Pichler W, Morisset M, Franck P, Marie B, Kohler C . T cell-mediated reactions to iodinated contrast media: evaluation by skin and lymphocyte activation tests. J Allergy Clin Immunol. 2005; 115(1):179-85. DOI: 10.1016/j.jaci.2004.09.012. View

20.

Nash K, Hafeez A, Hou S . Hospital-acquired renal insufficiency. Am J Kidney Dis. 2002; 39(5):930-6. DOI: 10.1053/ajkd.2002.32766. View