Trainor N, Whitwell H, Jimenez B, Addison K, Leonidou E, DiMaggio P
Commun Chem. 2024; 7(1):145.
PMID: 38937590
PMC: 11211345.
DOI: 10.1038/s42004-024-01227-x.
Brown A, Meiborg A, Franz-Wachtel M, Macek B, Gordon S, Rog O
Genetics. 2024; 227(1).
PMID: 38513719
PMC: 11075575.
DOI: 10.1093/genetics/iyae041.
Sbirkov Y, Schenk T, Kwok C, Stengel S, Brown R, Brown G
Front Cell Dev Biol. 2023; 11:1076458.
PMID: 37035245
PMC: 10076884.
DOI: 10.3389/fcell.2023.1076458.
Hanot M, Raby L, Volkel P, Le Bourhis X, Angrand P
Int J Mol Sci. 2023; 24(3).
PMID: 36768643
PMC: 9916924.
DOI: 10.3390/ijms24032322.
Levinsky A, McEdwards G, Sethna N, Currie M
Front Cell Dev Biol. 2022; 10:1026406.
PMID: 36568972
PMC: 9768651.
DOI: 10.3389/fcell.2022.1026406.
PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing.
Fong K, Zhao J, Lu X, Kim J, Piunti A, Shilatifard A
Mol Cell. 2022; 82(24):4611-4626.e7.
PMID: 36476474
PMC: 9812274.
DOI: 10.1016/j.molcel.2022.11.010.
De novo methylation of histone H3K23 by the methyltransferases EHMT1/GLP and EHMT2/G9a.
Vinson D, Stephens K, OMeally R, Bhat S, Dancy B, Cole R
Epigenetics Chromatin. 2022; 15(1):36.
PMID: 36411491
PMC: 9677696.
DOI: 10.1186/s13072-022-00468-1.
PARP3 supervises G9a-mediated repression of adhesion and hypoxia-responsive genes in glioblastoma cells.
Nguekeu-Zebaze L, Hanini N, Noll A, Wadier N, Ame J, Roegel L
Sci Rep. 2022; 12(1):15534.
PMID: 36109561
PMC: 9478127.
DOI: 10.1038/s41598-022-19525-6.
Demethylation of H3K9 and H3K27 Contributes to the Tubular Renal Damage Triggered by Endoplasmic Reticulum Stress.
Diaz-Bulnes P, Saiz M, Corte-Iglesias V, Rodrigues-Diez R, Florez A, Bernet C
Antioxidants (Basel). 2022; 11(7).
PMID: 35883846
PMC: 9312208.
DOI: 10.3390/antiox11071355.
Maternal EHMT2 is essential for homologous chromosome segregation by regulating transcription in oocyte meiosis.
Meng T, Lei W, Lu X, Liu X, Ma X, Nie X
Int J Biol Sci. 2022; 18(11):4513-4531.
PMID: 35864958
PMC: 9295060.
DOI: 10.7150/ijbs.75298.
Lysine methyltransferase inhibitors: where we are now.
Feoli A, Viviano M, Cipriano A, Milite C, Castellano S, Sbardella G
RSC Chem Biol. 2022; 3(4):359-406.
PMID: 35441141
PMC: 8985178.
DOI: 10.1039/d1cb00196e.
Histone 3 Lysine 27 Trimethylation Signature in Breast Cancer.
Borkiewicz L
Int J Mol Sci. 2021; 22(23).
PMID: 34884658
PMC: 8657745.
DOI: 10.3390/ijms222312853.
Loss of Polycomb Repressive Complex 2 Function Alters Digestive Organ Homeostasis and Neuronal Differentiation in Zebrafish.
Raby L, Volkel P, Hasanpour S, Cicero J, Toillon R, Adriaenssens E
Cells. 2021; 10(11).
PMID: 34831364
PMC: 8620594.
DOI: 10.3390/cells10113142.
Structure, Activity, and Function of the Protein Lysine Methyltransferase G9a.
Poulard C, Noureddine L, Pruvost L, Le Romancer M
Life (Basel). 2021; 11(10).
PMID: 34685453
PMC: 8541646.
DOI: 10.3390/life11101082.
Loss of a 7q gene, CUX1, disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms.
Imgruet M, Lutze J, An N, Hu B, Khan S, Kurkewich J
Blood. 2021; 138(9):790-805.
PMID: 34473231
PMC: 8414261.
DOI: 10.1182/blood.2020009195.
PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.
Zhang Q, Agius S, Flanigan S, Uckelmann M, Levina V, Owen B
Nat Commun. 2021; 12(1):4592.
PMID: 34321472
PMC: 8319299.
DOI: 10.1038/s41467-021-24866-3.
PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome.
Meng T, Zhou Q, Ma X, Liu X, Meng Q, Huang X
Nat Commun. 2020; 11(1):6354.
PMID: 33311485
PMC: 7733509.
DOI: 10.1038/s41467-020-20242-9.
A WIZ/Cohesin/CTCF Complex Anchors DNA Loops to Define Gene Expression and Cell Identity.
Justice M, Carico Z, Stefan H, Dowen J
Cell Rep. 2020; 31(2):107503.
PMID: 32294452
PMC: 7212317.
DOI: 10.1016/j.celrep.2020.03.067.
The association and prognostic impact of enhancer of zeste homologue 2 expression and epithelial-mesenchymal transition in resected lung adenocarcinoma.
Matsubara T, Toyokawa G, Takada K, Kinoshita F, Kozuma Y, Akamine T
PLoS One. 2019; 14(5):e0215103.
PMID: 31042721
PMC: 6493717.
DOI: 10.1371/journal.pone.0215103.
Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure.
Milite C, Feoli A, Horton J, Rescigno D, Cipriano A, Pisapia V
J Med Chem. 2019; 62(5):2666-2689.
PMID: 30753076
PMC: 7430049.
DOI: 10.1021/acs.jmedchem.8b02008.
