Diagnosis of Allergy and Asthma in Childhood

Overview

Journal Curr Allergy Asthma Rep

Specialties Allergy & Immunology
Pulmonary Medicine

Date 2010 Nov 6

PMID 21052877

Citations 6

Authors

Carlos E Baena-Cagnani

Hector A Badellino

Affiliations

Soon will be listed here.

Abstract

Childhood asthma is a widespread health problem because of its epidemic prevalence, as asthma affects more than 300 million people worldwide. Results from cross-sectional and cohort studies show that asthma starts in childhood in a large proportion of cases. A proper diagnosis is easier to make in adults and school-age children, as permanent changes in lung development, the strong impact of environmental factors on the airways, the immunologic maturity process, and the use of some diagnostic tools make asthma more difficult to diagnose in preschool children. This period of a child's life is an interesting challenge for pediatricians and specialists. The aim of the present review is to analyze the current knowledge regarding making an early and accurate asthma diagnosis and therefore deciding on the correct treatment to gain control over asthma symptoms and minimize health risks.

Citing Articles

Association of sugar-sweetened beverage intake frequency and asthma among U.S. adults, 2013.

Park S, Akinbami L, McGuire L, Blanck H Prev Med. 2016; 91:58-61.

PMID: 27496394 PMC: 5050122. DOI: 10.1016/j.ypmed.2016.08.004.

Role of exhaled nitric oxide as a predictor of atopy.

Romero K, Robinson C, Baumann L, Gilman R, Hamilton R, Hansel N Respir Res. 2013; 14:48.

PMID: 23639047 PMC: 3654880. DOI: 10.1186/1465-9921-14-48.

Diurnal temperature range and childhood asthma: a time-series study.

Xu Z, Huang C, Su H, Turner L, Qiao Z, Tong S Environ Health. 2013; 12:12.

PMID: 23374669 PMC: 3599100. DOI: 10.1186/1476-069X-12-12.

Regular-soda intake independent of weight status is associated with asthma among US high school students.

Park S, Blanck H, Sherry B, Jones S, Pan L J Acad Nutr Diet. 2012; 113(1):106-11.

PMID: 23260727 PMC: 4470486. DOI: 10.1016/j.jand.2012.09.020.

Climate change and children's health--a call for research on what works to protect children.

Xu Z, Sheffield P, Hu W, Su H, Yu W, Qi X Int J Environ Res Public Health. 2012; 9(9):3298-316.

PMID: 23202687 PMC: 3499869. DOI: 10.3390/ijerph9093298.

References

Spycher B, Silverman M, Barben J, Eber E, Guinand S, Levy M . A disease model for wheezing disorders in preschool children based on clinicians' perceptions. PLoS One. 2010; 4(12):e8533. PMC: 2795203. DOI: 10.1371/journal.pone.0008533. View

Turner S, Palmer L, Rye P, Gibson N, Judge P, Cox M . The relationship between infant airway function, childhood airway responsiveness, and asthma. Am J Respir Crit Care Med. 2004; 169(8):921-7. DOI: 10.1164/rccm.200307-891OC. View

Guerra S, Martinez F . Epidemiology of the origins of airflow limitation in asthma. Proc Am Thorac Soc. 2009; 6(8):707-11. PMC: 2797072. DOI: 10.1513/pats.200908-085DP. View

Piippo-Savolainen E, Korppi M . Long-term outcomes of early childhood wheezing. Curr Opin Allergy Clin Immunol. 2009; 9(3):190-6. DOI: 10.1097/ACI.0b013e32832ac00b. View

van de Kant K, Klaassen E, Jobsis Q, Nijhuis A, van Schayck O, Dompeling E . Early diagnosis of asthma in young children by using non-invasive biomarkers of airway inflammation and early lung function measurements: study protocol of a case-control study. BMC Public Health. 2009; 9:210. PMC: 2711088. DOI: 10.1186/1471-2458-9-210. View

Saglani S, Bush A . Asthma in preschool children: the next challenge. Curr Opin Allergy Clin Immunol. 2009; 9(2):141-5. PMC: 4254141. DOI: 10.1097/ACI.0b013e3283292230. View

Halvorsen R, Jenner A, Hagelin E, Borres M . Phadiatop infant in the diagnosis of atopy in children with allergy-like symptoms. Int J Pediatr. 2009; 2009:460737. PMC: 2778347. DOI: 10.1155/2009/460737. View

Castro-Rodriguez J, Garcia-Marcos L . Wheezing and Asthma in childhood: an epidemiology approach. Allergol Immunopathol (Madr). 2008; 36(5):280-90. DOI: 10.1016/s0301-0546(08)75224-8. View

Martinez F . Genes, environments, development and asthma: a reappraisal. Eur Respir J. 2007; 29(1):179-84. DOI: 10.1183/09031936.00087906. View

10.

Roberts G . Predicting the long-term outcome of preschool wheeze: are we there yet?. J Allergy Clin Immunol. 2009; 124(5):911-2. DOI: 10.1016/j.jaci.2009.09.034. View

11.

Guerra S, Sherrill D, Kurzius-Spencer M, Venker C, Halonen M, Quan S . The course of persistent airflow limitation in subjects with and without asthma. Respir Med. 2008; 102(10):1473-82. PMC: 2629140. DOI: 10.1016/j.rmed.2008.04.011. View

12.

Schultz A, Devadason S, Savenije O, Sly P, Le Souef P, Brand P . The transient value of classifying preschool wheeze into episodic viral wheeze and multiple trigger wheeze. Acta Paediatr. 2009; 99(1):56-60. DOI: 10.1111/j.1651-2227.2009.01508.x. View

13.

Taylor D, Bateman E, Boulet L, Boushey H, Busse W, Casale T . A new perspective on concepts of asthma severity and control. Eur Respir J. 2008; 32(3):545-54. DOI: 10.1183/09031936.00155307. View

14.

Brand P, Baraldi E, Bisgaard H, Boner A, Castro-Rodriguez J, Custovic A . Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J. 2008; 32(4):1096-110. DOI: 10.1183/09031936.00002108. View

15.

Holloway J, H Arshad S, Holgate S . Using genetics to predict the natural history of asthma?. J Allergy Clin Immunol. 2010; 126(2):200-9. DOI: 10.1016/j.jaci.2010.06.006. View

16.

Dallinga J, Robroeks C, van Berkel J, Moonen E, Godschalk R, Jobsis Q . Volatile organic compounds in exhaled breath as a diagnostic tool for asthma in children. Clin Exp Allergy. 2009; 40(1):68-76. DOI: 10.1111/j.1365-2222.2009.03343.x. View

17.

Castro-Rodriguez J, Holberg C, Wright A, Martinez F . A clinical index to define risk of asthma in young children with recurrent wheezing. Am J Respir Crit Care Med. 2000; 162(4 Pt 1):1403-6. DOI: 10.1164/ajrccm.162.4.9912111. View

18.

Henderson J, Granell R, Heron J, Sherriff A, Simpson A, Woodcock A . Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood. Thorax. 2008; 63(11):974-80. PMC: 2582336. DOI: 10.1136/thx.2007.093187. View

19.

Kusel M, de Klerk N, Kebadze T, Vohma V, Holt P, Johnston S . Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma. J Allergy Clin Immunol. 2007; 119(5):1105-10. PMC: 7125611. DOI: 10.1016/j.jaci.2006.12.669. View

20.

Baena-Cagnani C, Rossi G, Canonica G . Airway remodelling in children: when does it start?. Curr Opin Allergy Clin Immunol. 2007; 7(2):196-200. DOI: 10.1097/ACI.0b013e328082559a. View