Predictive Complication Factors for CT-guided Fine Needle Aspiration Biopsy of Pulmonary Lesions

Overview

Journal Clinics (Sao Paulo)

Publisher Elsevier

Specialty General Medicine

Date 2010 Nov 5

PMID 21049211

Citations 10

Authors

Marcos Duarte Guimaraes

Marcony Queiroz de Andrade

Alexandre Calabria da Fonte

Gustavo Benevides

Rubens Chojniak

Jefferson Luiz Gross

Affiliations

Soon will be listed here.

Abstract

Objective: Distinct aspects can influence the complication rates of computed tomography-guided percutaneous fine needle aspiration biopsy of lung lesions. The purpose of the current study is to determine the influence of radiological techniques and clinical characteristics in predicting complications from this procedure.

Subjects And Methods: A retrospective study was developed involving 340 patients who were submitted to a consecutive series of 362 computed tomography-guided fine needle aspiration biopsies of lung lesions between July 1996 and June 2004, using 22-gauge needles (CHIBA). Variables such as the radiological characteristics of the lesions, secondary pulmonary radiological findings, co-morbidities, and aspects concerning the procedure were studied.

Results: The diameters of the lung lesions varied from 9 to 140 mm, with a mean of 51.5 ± 24.3 mm and median of 40mm. The depth of the lesions varied from 10 mm to 130 mm, with a mean of 44 ± 20.9mm, and median median of 52 mm. Complications occurred in 52 (14.4%) cases, pneumothorax being the most frequent, with 40 (11.1%) cases, followed by hemoptisis with 7 (1.9%) cases, and hematoma with 4 (1.1%) cases. Lesions that did not contact the pleura, with normal pulmonary tissue interposition between lesion and pleura, had higher complication rates, with 22 (22%) cases, than lesions that contact the pleura, with 6 (9%) cases, with a statistically significant difference (p = 0.03).

Conclusions: CT-guided percutaneous fine needle aspiration biopsy of lung lesions had a lower rate of complications in our study and presented more rates of complications on lesions that lack pleural contact.

Citing Articles

Optimizing Precision: A Trajectory Tract Reference Approach to Minimize Complications in CT-Guided Transthoracic Core Biopsy.

Tsai S, Wu T, Lin F Diagnostics (Basel). 2024; 14(8).

PMID: 38667442 PMC: 11048995. DOI: 10.3390/diagnostics14080796.

Role of Fine Needle Aspiration Cytology in the Rapid Diagnosis of Pulmonary Infections in Renal Allograft Recipients with Respiratory Failure.

Selhi P, Chahal H, Wadhwa H, Kaur S, Selhi K, Kaur H Indian J Nephrol. 2023; 33(4):270-276.

PMID: 37781561 PMC: 10503569. DOI: 10.4103/ijn.ijn_249_22.

Feasibility and safety of fine positioning needle-mediated breathing control in CT-guided percutaneous puncture of small lung/liver nodules adjacent to diaphragm.

Wu Q, Cao B, Zheng Y, Liang B, Liu M, Wang L Sci Rep. 2021; 11(1):3411.

PMID: 33564042 PMC: 7873283. DOI: 10.1038/s41598-021-83036-z.

Feasibility, safety, and adequacy of research biopsies for cancer clinical trials at an academic medical center.

Lee K, Lee S, Yoon S, Ryoo B, Kim S, Choi S PLoS One. 2019; 14(8):e0221065.

PMID: 31404103 PMC: 6690517. DOI: 10.1371/journal.pone.0221065.

Complications of CT-guided lung biopsy with a non-coaxial semi-automated 18 gauge biopsy system: Frequency, severity and risk factors.

Elshafee A, Karch A, Ringe K, Shin H, Raatschen H, Soliman N PLoS One. 2019; 14(3):e0213990.

PMID: 30883575 PMC: 6422294. DOI: 10.1371/journal.pone.0213990.

References

Austin J, Cohen M . Value of having a cytopathologist present during percutaneous fine-needle aspiration biopsy of lung: report of 55 cancer patients and metaanalysis of the literature. AJR Am J Roentgenol. 1993; 160(1):175-7. DOI: 10.2214/ajr.160.1.8416620. View

Greif J, Marmur S, Schwarz Y, Man A, Staroselsky A . Percutaneous core cutting needle biopsy compared with fine-needle aspiration in the diagnosis of peripheral lung malignant lesions: results in 156 patients. Cancer. 1998; 84(3):144-7. DOI: 10.1002/(sici)1097-0142(19980625)84:3<144::aid-cncr4>3.0.co;2-o. View

Chojniak R, Isberner R, Viana L, Yu L, Aita A, Soares F . Computed tomography guided needle biopsy: experience from 1,300 procedures. Sao Paulo Med J. 2006; 124(1):10-4. PMC: 11060400. DOI: 10.1590/s1516-31802006000100003. View

Arslan S, Yilmaz A, Bayramgurler B, Uzman O, Nver E, Akkaya E . CT- guided transthoracic fine needle aspiration of pulmonary lesions: accuracy and complications in 294 patients. Med Sci Monit. 2002; 8(7):CR493-7. View

Yankelevitz D, Henschke C, Koizumi J, Altorki N, LIBBY D . CT-guided transthoracic needle biopsy of small solitary pulmonary nodules. Clin Imaging. 1997; 21(2):107-10. DOI: 10.1016/s0899-7071(96)00011-3. View

Wallace M, Krishnamurthy S, Broemeling L, Gupta S, Ahrar K, Morello Jr F . CT-guided percutaneous fine-needle aspiration biopsy of small (< or =1-cm) pulmonary lesions. Radiology. 2002; 225(3):823-8. DOI: 10.1148/radiol.2253011465. View

Conces Jr D, Schwenk Jr G, Doering P, Glant M . Thoracic needle biopsy. Improved results utilizing a team approach. Chest. 1987; 91(6):813-6. DOI: 10.1378/chest.91.6.813. View

Perlmutt L, Johnston W, Dunnick N . Percutaneous transthoracic needle aspiration: a review. AJR Am J Roentgenol. 1989; 152(3):451-5. DOI: 10.2214/ajr.152.3.451. View

Kazerooni E, Lim F, Mikhail A, Martinez F . Risk of pneumothorax in CT-guided transthoracic needle aspiration biopsy of the lung. Radiology. 1996; 198(2):371-5. DOI: 10.1148/radiology.198.2.8596834. View

10.

Romano M, Griffo S, Gentile M, Mainenti P, Tamburrini O, Iaccarino V . CT guided percutaneous fine needle biopsy of small lung lesions in outpatients. Safety and efficacy of the procedure compared to inpatients. Radiol Med. 2004; 108(3):275-82. View

11.

Kucuk C, Yilmaz A, Yilmaz A, Akkaya E . Computed tomography-guided transthoracic fine-needle aspiration in diagnosis of lung cancer: a comparison of single-pass needle and multiple-pass coaxial needle systems and the value of immediate cytological assessment. Respirology. 2004; 9(3):392-6. DOI: 10.1111/j.1440-1843.2004.00607.x. View

12.

Guimaraes M, Chojniak R, Gross J, Bitencourt A . Predictive success factors for CT-guided fine needle aspiration biopsy of pulmonary lesions. Clinics (Sao Paulo). 2009; 64(12):1139-44. PMC: 2797581. DOI: 10.1590/S1807-59322009001200002. View

13.

Vitulo P, Dore R, Cerveri I, Tinelli C, Cremaschi P . The role of functional respiratory tests in predicting pneumothorax during lung needle biopsy. Chest. 1996; 109(3):612-5. DOI: 10.1378/chest.109.3.612. View

14.

Li H, Boiselle P, Shepard J, Trotman-Dickenson B, McLoud T . Diagnostic accuracy and safety of CT-guided percutaneous needle aspiration biopsy of the lung: comparison of small and large pulmonary nodules. AJR Am J Roentgenol. 1996; 167(1):105-9. DOI: 10.2214/ajr.167.1.8659351. View

15.

Miller J, Pramanik B, Lavenhar M . Predicting the rates of success and complications of computed tomography-guided percutaneous core-needle biopsies of the thorax from the findings of the preprocedure chest computed tomography scan. J Thorac Imaging. 1998; 13(1):7-13. DOI: 10.1097/00005382-199801000-00003. View

16.

van Sonnenberg E, Casola G, DAgostino H, Goodacre B, Sanchez R . Interventional radiology in the chest. Chest. 1992; 102(2):608-12. DOI: 10.1378/chest.102.2.608. View

17.

Ng Y, Patsios D, Roberts H, Walsham A, Paul N, Chung T . CT-guided percutaneous fine-needle aspiration biopsy of pulmonary nodules measuring 10 mm or less. Clin Radiol. 2008; 63(3):272-7. DOI: 10.1016/j.crad.2007.09.003. View

18.

Lourenco R, Camacho R, Barata M, Canario D, Gaspar A, Cyrne C . CT-guided percutaneous transthoracic biopsy in the evaluation of undetermined pulmonary lesions. Rev Port Pneumol. 2006; 12(5):503-24. View

19.

Yu L, Deheinzelin D, Younes R, Chojniak R . Computed tomography-guided cutting needle biopsy of pulmonary lesions. Rev Hosp Clin Fac Med Sao Paulo. 2002; 57(1):15-8. DOI: 10.1590/s0041-87812002000100003. View