Short-term Outcomes Following Laparoscopic Resection for Colon Cancer

Overview

Journal Int J Colorectal Dis

Specialties Gastroenterology
General Surgery

Date 2010 Oct 26

PMID 20972571

Citations 8

Authors

Dara O Kavanagh

David Gibson

Diarmaid C Moran

Myles Smith

Kate O Donnell

Emmanuel Eguare

Frank B V Keane

Diarmaid S O Riordain

Paul C Neary

Affiliations

Soon will be listed here.

Abstract

Background: Laparoscopic resection for colon cancer has been proven to have a similar oncological efficacy compared to open resection. Despite this, it is performed by a minority of colorectal surgeons. The aim of our study was to evaluate the short-term clinical, oncological and survival outcomes in all patients undergoing laparoscopic resection for colon cancer.

Methods: From July 2005 to December 2008, 202 consecutive patients underwent laparoscopic resection for colon cancer. Surgery was analysed on an intention to treat basis. The mean follow-up was 24.3 months.

Results: Two hundred twenty-two patients underwent resection for colon cancer. Two hundred two underwent laparoscopic resection (91%). One hundred sixteen were male patients. Mean age was 65.9 years (range = 24-91). The median length of stay was 6.6 days (mean = 7.1 days). One hundred eighty-eight of 202 (93.1%) were completed laparoscopically. Fourteen (6.9%) were converted. The overall morbidity rate was 15.8%. There were three clinically apparent anastomotic leaks. The 30-day mortality was 1 (0.5%). The mean nodal yield was 13.4 (range = 8-37) nodes. There were no positive margins detected. Overall survival in laparoscopically treated colon cancer was 88.1%. In those patients with non-metastatic disease, the overall survival was 90.7% (165/182).

Conclusion: Laparoscopic resection for colon cancer is achievable in 85% (188/222) of patients. This facilitates adequate oncological clearance. It is associated with a low morbidity rate and favourable short-term survival outcomes. This data reflects the potential outcomes dedicated MIS colorectal units will have to offer colon cancer patients once laparoscopic colorectal surgery becomes the de facto surgical approach.

Citing Articles

Surgical and Oncological Outcome of Laparoscopic Resection of Colorectal Cancers: A Single-Center Experience.

Muhammed S, Asad N, Dewana A, Ahmed B, Al-Dabbagh A Cureus. 2024; 16(4):e58849.

PMID: 38784322 PMC: 11115474. DOI: 10.7759/cureus.58849.

Development and Validation of a Homemade, Low-Cost Laparoscopic Simulator for Resident Surgeons (LABOT).

Soriero D, Atzori G, Barra F, Pertile D, Massobrio A, Conti L Int J Environ Res Public Health. 2020; 17(1).

PMID: 31906532 PMC: 6981870. DOI: 10.3390/ijerph17010323.

C-reactive protein in predicting major postoperative complications are there differences in open and minimally invasive colorectal surgery? Substudy from a randomized clinical trial.

Straatman J, Cuesta M, Tuynman J, Veenhof A, Bemelman W, van der Peet D Surg Endosc. 2017; 32(6):2877-2885.

PMID: 29282574 PMC: 5956066. DOI: 10.1007/s00464-017-5996-9.

Total laparoscopic right hemicolectomy with 3-step stapled intracorporeal isoperistaltic ileocolic anastomosis for colon cancer: An evaluation of short-term outcomes.

Jian-Cheng T, Shu-Sheng W, Bo Z, Jian F, Liang Z Medicine (Baltimore). 2016; 95(48):e5538.

PMID: 27902621 PMC: 5134775. DOI: 10.1097/MD.0000000000005538.

Homemade laparoscopic surgical simulator: a cost-effective solution to the challenge of acquiring laparoscopic skills?.

Aslam A, Nason G, Giri S Ir J Med Sci. 2015; 185(4):791-796.

PMID: 26377602 DOI: 10.1007/s11845-015-1357-7.

References

Schwenk W, Bohm B, Muller J . Postoperative pain and fatigue after laparoscopic or conventional colorectal resections. A prospective randomized trial. Surg Endosc. 1998; 12(9):1131-6. DOI: 10.1007/s004649900799. View

Scala A, Huang A, Dowson H, Rockall T . Laparoscopic colorectal surgery - results from 200 patients. Colorectal Dis. 2007; 9(8):701-5. DOI: 10.1111/j.1463-1318.2006.01198.x. View

Mehigan B, White A, Winter D, Sheehan K, Hyland J . Laparoscopic colorectal resection: initial experience in a specialist unit. Ir Med J. 2006; 99(7):211, 213-4. View

Nelson H, Sargent D, Wieand H, Fleshman J, Anvari M, Stryker S . A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med. 2004; 350(20):2050-9. DOI: 10.1056/NEJMoa032651. View

Jacobs M, Verdeja J, GOLDSTEIN H . Minimally invasive colon resection (laparoscopic colectomy). Surg Laparosc Endosc. 1991; 1(3):144-50. View

Lacy A, Garcia-Valdecasas J, Delgado S, Castells A, Taura P, Pique J . Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet. 2002; 359(9325):2224-9. DOI: 10.1016/S0140-6736(02)09290-5. View

Buunen M, Veldkamp R, Hop W, Kuhry E, Jeekel J, Haglind E . Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol. 2008; 10(1):44-52. DOI: 10.1016/S1470-2045(08)70310-3. View

Mirza M, Longman R, Farrokhyar F, Sheffield J, Kennedy R . Long-term outcomes for laparoscopic versus open resection of nonmetastatic colorectal cancer. J Laparoendosc Adv Surg Tech A. 2008; 18(5):679-85. DOI: 10.1089/lap.2007.0169. View

Lordan J, Tilney H, Shirol S, Jourdan I, Gudgeon A . Does the laparoscopic colorectal surgery learning curve adversely affect the results of colorectal cancer resection? A 3-year prospective study in a district general hospital. Colorectal Dis. 2007; 10(4):363-9. DOI: 10.1111/j.1463-1318.2007.01332.x. View

10.

Buchanan G, Malik A, Parvaiz A, Sheffield J, Kennedy R . Laparoscopic resection for colorectal cancer. Br J Surg. 2008; 95(7):893-902. DOI: 10.1002/bjs.6019. View

11.

Liang J, Huang K, Lai H, Lee P, Jeng Y . Oncologic results of laparoscopic versus conventional open surgery for stage II or III left-sided colon cancers: a randomized controlled trial. Ann Surg Oncol. 2006; 14(1):109-17. DOI: 10.1245/s10434-006-9135-4. View

12.

Stocchi L, Nelson H . Laparoscopic colectomy for colon cancer: trial update. J Surg Oncol. 1998; 68(4):255-67. DOI: 10.1002/(sici)1096-9098(199808)68:4<255::aid-jso10>3.0.co;2-z. View

13.

Young-Fadok T . Colon cancer: trials, results, techniques (LAP and HALS), future. J Surg Oncol. 2007; 96(8):651-9. DOI: 10.1002/jso.20921. View

14.

Jemal A, Murray T, Samuels A, Ghafoor A, Ward E, Thun M . Cancer statistics, 2003. CA Cancer J Clin. 2003; 53(1):5-26. DOI: 10.3322/canjclin.53.1.5. View

15.

Baker R, Titu L, Hartley J, Lee P, Monson J . A case-control study of laparoscopic right hemicolectomy vs. open right hemicolectomy. Dis Colon Rectum. 2004; 47(10):1675-9. DOI: 10.1007/s10350-004-0655-3. View

16.

Raymond T, Kumar S, Dastur J, Adamek J, Khot U, Stewart M . Case controlled study of the hospital stay and return to full activity following laparoscopic and open colorectal surgery before and after the introduction of an enhanced recovery programme. Colorectal Dis. 2009; 12(10):1001-6. DOI: 10.1111/j.1463-1318.2009.01925.x. View

17.

Kuhry E, Schwenk W, Gaupset R, Romild U, Bonjer H . Long-term results of laparoscopic colorectal cancer resection. Cochrane Database Syst Rev. 2008; (2):CD003432. PMC: 7017639. DOI: 10.1002/14651858.CD003432.pub2. View

18.

Boyle E, Ridgway P, Keane F, Neary P . Laparoscopic colonic resection in inflammatory bowel disease: minimal surgery, minimal access and minimal hospital stay. Colorectal Dis. 2008; 10(9):911-5. DOI: 10.1111/j.1463-1318.2008.01518.x. View

19.

Jayne D, Guillou P, Thorpe H, Quirke P, Copeland J, Smith A . Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group. J Clin Oncol. 2007; 25(21):3061-8. DOI: 10.1200/JCO.2006.09.7758. View

20.

Lengyel J, Morrison C, Sagar P . Trends towards increased use of the laparoscopic approach in colorectal surgery. Colorectal Dis. 2009; 12(10):1007-12. DOI: 10.1111/j.1463-1318.2009.01937.x. View