EGFs and ERBBs--brief History and Prospects

Overview

Journal Semin Cell Dev Biol

Specialties Cell Biology
Reproductive Medicine

Date 2010 Oct 26

PMID 20970513

Citations 1

Authors

David F Stern

Affiliations

Soon will be listed here.

Citing Articles

Overexpression of ERBB4 JM-a CYT-1 and CYT-2 isoforms in transgenic mice reveals isoform-specific roles in mammary gland development and carcinogenesis.

Wali V, Gilmore-Hebert M, Mamillapalli R, Haskins J, Kurppa K, Elenius K Breast Cancer Res. 2014; 16(6):501.

PMID: 25516216 PMC: 4303208. DOI: 10.1186/s13058-014-0501-z.

References

Hunter T, Cooper J . Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells. Cell. 1981; 24(3):741-52. DOI: 10.1016/0092-8674(81)90100-8. View

Ding L, Getz G, Wheeler D, Mardis E, McLellan M, Cibulskis K . Somatic mutations affect key pathways in lung adenocarcinoma. Nature. 2008; 455(7216):1069-75. PMC: 2694412. DOI: 10.1038/nature07423. View

Sordella R, Bell D, Haber D, Settleman J . Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science. 2004; 305(5687):1163-7. DOI: 10.1126/science.1101637. View

Shilo B . Regulating the dynamics of EGF receptor signaling in space and time. Development. 2005; 132(18):4017-27. DOI: 10.1242/dev.02006. View

Anzano M, Roberts A, Meyers C, Komoriya A, Lamb L, Smith J . Synergistic interaction of two classes of transforming growth factors from murine sarcoma cells. Cancer Res. 1982; 42(11):4776-8. View

Bao J, Wolpowitz D, Role L, Talmage D . Back signaling by the Nrg-1 intracellular domain. J Cell Biol. 2003; 161(6):1133-41. PMC: 2172983. DOI: 10.1083/jcb.200212085. View

Riese 2nd D, van Raaij T, Plowman G, ANDREWS G, Stern D . The cellular response to neuregulins is governed by complex interactions of the erbB receptor family. Mol Cell Biol. 1995; 15(10):5770-6. PMC: 230829. DOI: 10.1128/MCB.15.10.5770. View

Muraoka-Cook R, Sandahl M, Strunk K, Miraglia L, Husted C, Hunter D . ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo. Mol Cell Biol. 2009; 29(18):4935-48. PMC: 2738276. DOI: 10.1128/MCB.01705-08. View

Scott J, Patterson S, Rall L, Bell G, Crawford R, Penschow J . The structure and biosynthesis of epidermal growth factor precursor. J Cell Sci Suppl. 1985; 3:19-28. DOI: 10.1242/jcs.1985.supplement_3.3. View

10.

Anderson D, Koch C, Grey L, Ellis C, Moran M, Pawson T . Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors. Science. 1990; 250(4983):979-82. DOI: 10.1126/science.2173144. View

11.

Manning G, Whyte D, Martinez R, Hunter T, Sudarsanam S . The protein kinase complement of the human genome. Science. 2002; 298(5600):1912-34. DOI: 10.1126/science.1075762. View

12.

Baselga J, Gelmon K, Verma S, Wardley A, Conte P, Miles D . Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy. J Clin Oncol. 2010; 28(7):1138-44. PMC: 4979216. DOI: 10.1200/JCO.2009.24.2024. View

13.

Scaltriti M, Chandarlapaty S, Prudkin L, Aura C, Jimenez J, Angelini P . Clinical benefit of lapatinib-based therapy in patients with human epidermal growth factor receptor 2-positive breast tumors coexpressing the truncated p95HER2 receptor. Clin Cancer Res. 2010; 16(9):2688-95. PMC: 3243489. DOI: 10.1158/1078-0432.CCR-09-3407. View

14.

Bitler B, Goverdhan A, Schroeder J . MUC1 regulates nuclear localization and function of the epidermal growth factor receptor. J Cell Sci. 2010; 123(Pt 10):1716-23. PMC: 2864713. DOI: 10.1242/jcs.062661. View

15.

Wang Y, Yamaguchi H, Hsu J, Hung M . Nuclear trafficking of the epidermal growth factor receptor family membrane proteins. Oncogene. 2010; 29(28):3997-4006. PMC: 2904849. DOI: 10.1038/onc.2010.157. View

16.

Ni C, Murphy M, Golde T, Carpenter G . gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science. 2001; 294(5549):2179-81. DOI: 10.1126/science.1065412. View

17.

Jura N, Endres N, Engel K, Deindl S, Das R, Lamers M . Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell. 2009; 137(7):1293-307. PMC: 2814540. DOI: 10.1016/j.cell.2009.04.025. View

18.

Fry W, Kotelawala L, Sweeney C, Carraway 3rd K . Mechanisms of ErbB receptor negative regulation and relevance in cancer. Exp Cell Res. 2008; 315(4):697-706. PMC: 2667444. DOI: 10.1016/j.yexcr.2008.07.022. View

19.

Masui H, Kawamoto T, Sato J, Wolf B, Sato G, Mendelsohn J . Growth inhibition of human tumor cells in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies. Cancer Res. 1984; 44(3):1002-7. View

20.

Silberberg G, Darvasi A, Pinkas-Kramarski R, Navon R . The involvement of ErbB4 with schizophrenia: association and expression studies. Am J Med Genet B Neuropsychiatr Genet. 2006; 141B(2):142-8. DOI: 10.1002/ajmg.b.30275. View